Reported effects of some oncogenes, tumour suppressor genes and DNA repair genes on sensitivity of cells to ionizing radiation are reviewed.
综述了一些癌基因、肿瘤抑制基因和DNA修复基因对细胞电离辐射敏感性的影响。
The results confirmed that the alcohol (ethanol) was being converted to acetaldehyde, causing DNA damage and switching on the cell's DNA repair genes.
结果表明，酒精(乙醇)转换成乙醛后破坏dna，激活细胞内dna的修复基因。
Objective To explore the association between genetic polymorphisms of DNA repair genes XRCC1 , XRCC3 and susceptibility to chronic benzene poisoning.
目的探讨DNA修复基因XRCC1、XRCC3多态性与慢性苯中毒遗传易感性的关联及其与慢性苯中毒潜伏期的关系。
Objectives to detect the expression of DNA repair genes in primary glioma tissues by low-density array, and to analyze the significance of the expression.
目的运用低密度表达谱芯片检测人脑原发胶质瘤组织中DNA损伤修复基因的表达情况，进一步分析其表达变化的意义。
Other genes in the collection have more-precise repair duties, fixing small nicks and mistakes in DNA.
研究中收集到的其他基因则承担着更精细的修复工作，比如修复dna的小伤口和错误。
To figure out why, the researchers analyzed which genes were being transcribed more as resistance developed, and identified several that are involved in DNA repair pathways.
为了找出原因，研究员分析了那种基因在获得耐药性是转录的最多，辨别几种参与了DNA修复途径。
Scientists have discovered how to edit DNA to repair 'broken genes' to cure incurable diseases - and potentially extend human lifespan.
科学家已经发现如何通过编辑DNA来修复“受损基因”，从而治愈绝症并有可能延长人类寿命。
One line of evidence supporting the connection is that defects in certain genes needed for DNA repair produce maladies that mimic those of accelerated aging.
支持这种关系的证据是需要修复的特定基因的损伤产生疾病例如加速衰老。
Objective To investigate the association of polymorphisms of metabolic and DNA repair enzyme genes and DNA damage in peripheral blood lymphocytes in coke-oven workers.
目的研究外源性化学物代谢酶和DNA损伤修复酶基因多态性与焦炉作业工人外周血淋巴细胞DNA损伤易感性的关系。
Scientists would alter these cells by inserting genes or activating the cells' DNA - repair mechanisms.
科学家通过注入基因或激活细胞的脱氧糖核酸(dna)修复机制来造基因。
Conclusions Some DNA replication, and damage repair genes associated with benzene poisoning show differential expression, which provides the basis for screening biomarkers of benzene poisoning.
结论苯中毒患者外周血白细胞的DNA复制及损伤修复基因与正常人相比存在差异性表达，为进一步筛选苯中毒生物标志物提供了依据。
Most members of the XRCC genes family participated in several DNA repair pathways, including base excision repair, homologous recombination repair and non-homologous end joining.
目前已鉴定的这一基因家族的多数成员均参与几种重要的DNA修复途径，包括碱基切除修复、同源重组修复和非同源末端重接。
Objective To screen DNA replication, and damage repair genes associated with benzene poisoning by using gene expression profile analysis.
目的筛选与苯中毒有关的DNA复制及损伤修复基因。
Looking at cells in a dish, the team found that mistakes in these genes prevented the cells from being able to repair damage to their DNA.
研究团队调查研究一个盘子里的细胞，发现这些基因的缺陷能够阻止细胞修复对它们DNA的损害。
Results The cDNA microarray results indicated that 12 out of 64 DNA repair related genes in HGC27 cells were down-regulated (inferior to 0.5 fold) and 6 genes was up-regulated (superior to 2 folds).
结果基因芯片分析显示，HGC27细胞的64对核修复相关基因中，12对基因表达水平下调至0.5以下，6对基因表达水平上调至2倍以上。
These genes were involved in cell proliferation, gene transcription, apoptosis, signal transduction, DNA damage and repair, tumor differentiation and metastasis, cell cycle, and so on.
这些基因分别与细胞增殖、基因转录、凋亡、信号转导、DNA损伤修复、肿瘤分化和浸润转移及细胞周期调节等相关。
This paper reviews epidemiology studies of associations between polymorphisms in genes involved in immunity regulation, chemical and folate metabolism, DNA repair, cell cycle and oncogenes and NHL.
虽然有一些研究发现基因多态性可以增加NHL发病的危险性，但还需要更多的流行病学研究。
Once the TP53 protein is activated, it can trigger the expression of several genes that influence cell cycle arrest and DNA repair or lead to apoptosis when DNA repair is failed.
一旦TP53蛋白被激活就能引发数种基因的表达来影响细胞周期阻滞、DNA修复、或者在DNA修复失败后引导凋亡发生。
The tumor suppressor p53 regulates cell cycle arrest, apoptosis and DNA repair processes by controlling various target genes that contain p53 sequence-specific DNA binding sites.
抑癌蛋白p53通过调节下游靶基因的转录，参与细胞凋亡、细胞周期抑制、DNA损伤修复等多种生物学过程。
The genes were generally classified according to their functions, apoptosis, cell cycle, cell growth, proliferation and differentiation and DNA repair were involved.
按功能将其进行大体分类，涉及到细胞凋亡、细胞周期、细胞生长增殖和分化、DNA修复等多方面。
The genes were generally classified according to their functions, apoptosis, cell cycle, cell growth, proliferation and differentiation and DNA repair were involved.
按功能将其进行大体分类，涉及到细胞凋亡、细胞周期、细胞生长增殖和分化、DNA修复等多方面。
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