Aim To prepare Clarithromycin floating beads and investigate its buoyancy, entrapment efficiency and drug release behavior in vitro.
目的制备克拉霉素胃漂浮小丸,考察其漂浮性,包封率和体外释药行为。
Conclusion: The HCPT-SSLN has high entrapment efficiency and drug loading, uniform particle size, good stability, which initially indicates that HCPT is fit for being incorporated into SSLN.
结论:本实验制备的HCPT - SSLN包封率和载药量较高,粒径分布均匀,稳定性良好。初步表明HCPT适合进行SSLN包裹。
Optimization of preparation and formulation was accomplished by evaluating the drug-loading amounts and the entrapment efficiency of luteolin liposomes.
方法采用薄膜分散法和冻干工艺进行木犀草素脂质体制备,并以载药量、包封率为评价指标,优化制备处方和工艺。
The drug loading, entrapment efficiency, diameter of nanoparticles and particle diameter distribution, shape and release curve of nanoparticles were investigated in vitro.
对纳米粒的载药量、大小及分布、形态及体外释放等进行了研究。
The results indicated that the microspheres had poor drug loading and entrapment efficiency abilities due to residual impurities contained in polymer.
初步分析表明,因聚合物中残留的微小杂质的影响,造成了所制备的载药微球过低的载药量及包封率。
METHODS The effect of cholesterol content, lipid-drug ratio, incubation time and temperature, and calcium acetate concentration on entrapment efficiency was studied.
方法以包封率为指标,考察阿魏酸脂质体胆固醇含量、脂药比、孵育时间、孵育温度、钙离子浓度等因素对包封率的影响。
The entrapment efficiency, drug load content, in vitro release and stability of Bre-CS-NP were studied.
并进行了灯盏花素壳聚糖纳米粒包封率、载药量、体外释放度、稳定性等试验研究。
The entrapment efficiency, drug load content, in vitro release and stability of Bre-CS-NP were studied.
并进行了灯盏花素壳聚糖纳米粒包封率、载药量、体外释放度、稳定性等试验研究。
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