Some of the teens had changed to one particular gene—the glucocorticoid receptor (GR)—that helps regulate the body's hormonal response to stress.
一些青少年已经转换了一个特定的基因——糖皮质激素受体（GR）——帮助调节体内荷尔蒙对于压力的反应。
RU486, an antagonist of glucocorticoid receptor (GR), did not affect these effects.
这些作用不能被糖皮质激素受体(GR)拮抗剂ru 486所阻断。
Novel 1,2,3,4-tetrahydroquinoxaline derivative having glucocorticoid receptor binding activity.
具有糖皮质激素受体结合活性的新型1，2，3，4-四氢喹喔啉衍生物。
When he made these 7 changes to the ancestral receptor, it behaved just like a new glucocorticoid receptor.
当研究人员改变早先的原始受体的这7个位点后，它就成为了一个新的糖皮质激素受体了。
The interactions between BAG-1 and glucocorticoid receptor(GR)were detected with immune co-precipitation.
免疫共沉淀法检测核蛋白中BAG-1与糖皮质激素受体（GR）的相互结合；
Conclusion: No correlation was found between glucocorticoid receptor gene in exon 2/1 codons 23 and asthma.
结论：江西籍汉族人种中糖皮质激素受体基因外显子2/1密码子23基因未发现多态性的存在。
It was reported that the glucocorticoid receptor played a key role in regulation of stress and inflammation response.
研究表明，糖皮质激素受体在应激反应和炎症反应的调控中起着非常重要的作用。
Objective to study the correlation between the rabbit glucocorticoid receptor (GR) and steroid induced glaucoma (SIG).
目的研究家兔糖皮质激素受体(GR)与激素性青光眼(SIG)的关系。
Glucocorticoid (GC) has been widely used now and it binds to glucocorticoid receptor (GR) to produce its biological effect.
糖皮质激素(GC)现已广泛用于临床，通过糖皮质激素受体(GR)介导产生生物效应。
The present invention is directed to compounds of Formula (I), or salt thereof, which are modulators of the glucocorticoid receptor.
本发明涉及式（I）的化合物或其盐，其是糖皮质激素的调节剂。
The present invention is directed to compounds of Formula I: (I) or salt thereof, which are modulators of the glucocorticoid receptor.
本发明涉及式（I）的化合物或其盐，其是糖皮质激素受体的调节剂。
The glucocorticoid receptor of hepatic cytosol of rat was determined by the exchange assay in the presence of endogenous corticosterone.
在内源性激素存在的条件下，用交换法测定了大鼠肝胞液的糖皮质激素受体。
For example, increased expression of the glucocorticoid receptor gene in particular brain regions improves the ability to regulate a stress response.
例如，糖皮质激素受体基因在大脑特定区域的持续表达提高了调节应激反应的能力。
Objective: to study on glucocorticoid receptor (GCR) activity of peripheral leukocytes in allergic rhinitis guinea-pigs with Cold or Heat Syndrome.
前言：目的：研究寒、热证豚鼠变应性鼻炎糖皮质激素受体(G CR)活性。
Maximal binding volume of glucocorticoid receptor (GR) in hepatic tissue was assayed by radio-ligand binding assay and protein content was assayed by Western blot.
肝组织GR采用放射性配体结合分析法测定其最大结合容量以及用免疫印迹法测定其蛋白含量。
Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding serine 211 of human glucocorticoid receptor.
该多克隆抗体通过用合成磷酸肽免疫动物制备，该合成磷酸肽是人糖皮质激素受体丝氨酸（211位）附近的残基。
The changes of glucocorticoid receptor (GR) and effects of early high-dose glucocorticoid (GC) application during cardiopulmonary bypass (CPB) were studied on the CPB model in rabbit.
本文应用兔体外循环(CPB)模型研究CPB中糖皮质激素受体(GR)的变化及早期应用大剂量糖皮质激素(GC)的效应。
Objective to study the effects of dexamethasone on the proliferation and differentiation of a human ovarian carcinoma cell line (3ao) and on the expression of glucocorticoid receptor (GR).
目的观察地塞米松调节人卵巢癌细胞系3ao细胞增殖分化的作用机制及3ao细胞中糖皮质激素受体(GR)的表达。
It is possible that glucocorticoid receptor down-regulation indicates disorders of stress response and also may be associated with altered immune status of patients with ACLF of different stages.
糖皮质激素受体的下调提示可能与患者机体应激反应紊乱，以及肝衰竭不同时期免疫状态的改变有关。
When glucocorticoid binds to its receptor in the hippocampus, that activates the expression of genes which dampen further synthesis of the hormone.
当糖皮质激素和海马体中的受体结合时，激活了那些阻止这种激素合成的基因。
This explains why levels of glucocorticoid-receptor protein are different in the two groups of rats.
这就可以解释为什么两组老鼠中的糖皮质激素受体蛋白水平会有差异。
The researchers went on to study what is responsible for the difference in expression of the glucocorticoid-receptor gene.
研究者们进一步探究是什么造成了糖皮质激素受体基因表达的差异。
They found that women abused during pregnancy were significantly more likely than others to have a child with methylated glucocorticoid-receptor genes.
研究发现，孕期中遭到虐待的母亲生下糖皮质激素受体基因被甲基化的幼儿的可能性要比其他母亲高出得多。
Taken together, these results suggest that glucocorticoid-receptor-gene methylation happens in the fetus in response to a mother's stress, and persists into adolescence.
总体看来，这些结论表明胎儿糖皮质激素受体基因的甲基化是由于母亲压力过大引起的，并且其影响将会持续到青春期。
Newborns whose mothers suffered from depression while they were pregnant are known to have more highly methylated glucocorticoid-receptor genes than others.
一些母亲在怀孕时一直处于忧伤抑郁的情绪中，她们的孩子在刚出生时甲基化糖皮质激素受体水平就远高于常人。
Their team examined the methylation of the glucocorticoid-receptor gene in a group of children ranging in age from ten to 19 years, and in those children's mothers.
他们的团队对一组10到19岁的儿童进行了糖皮质激素受体基因甲基化的检测，并对他们的妈妈做了同样的检测。
Rats that had experienced little maternal care showed high levels of methylation and low levels of acetylation of the glucocorticoid-receptor gene and its neighbouring proteins.
是否应该是 缺少关爱的老鼠糖皮质激素受体基因和 基因周边的蛋白质表现出高水平的甲基化及较低水平的乙酰化。 另，acetylation 是否应该是乙醇化？
Objective To observe the changes of expression of steroid receptor coactivators(SRC) during the early stage in the burned mice, and the mechanism of glucocorticoid resistance(GCR).
目的观察小鼠烧伤后早期类固醇受体辅活化子（SRC）蛋白表达的时相变化，初步探讨烧伤早期糖皮质激素抵抗的分子机制。
This suspicion was confirmed when he found it is also the case that the more maternal care a pup receives, the more NGFI-A it has bound to its glucocorticoid-receptor genes.
Szyf发现鼠仔接受的母性关怀越多，与糖皮质激素受体基因结合的NGFI -A就越多。这证实了他的猜想。
This suspicion was confirmed when he found it is also the case that the more maternal care a pup receives, the more NGFI-A it has bound to its glucocorticoid-receptor genes.
Szyf发现鼠仔接受的母性关怀越多，与糖皮质激素受体基因结合的NGFI -A就越多。这证实了他的猜想。
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