Objective: to establish the model of inbred strain rat heart heterotopic transplantation.
目的:建立近交系大鼠同种异位腹腔心脏移植动物模型。
Objective To establish the rapid and stable model of the heterotopic heart transplantation in rats.
目的建立一种快速、稳定的大鼠腹腔异位心脏移植模型。
Objective To provide a stable, convenient and easily observable model of heterotopic heart transplantation in rat, for further studies on transplantation immunology, pathology and organ protection.
目的为移植免疫、病理和器官保护等方面的实验研究提供操作简便、易于观察的大鼠心脏异位移植实验动物模型。
Methods Cervical heterotopic cardiac transplantation model of rat was established and pathological changes of transplanted heart were observed at different time point by he stain method.
方法建立大鼠颈部心脏移植模型,采用HE染色的方法,观察术后不同时间移植心脏的病理改变。
Objective on the rat model of heterotopic heart transplantation, the mechanism of immune tolerance induced by portal venous injection of donor spleen cells was studied.
目的利用大鼠异位心脏移植模型,探讨门静脉注射供体脾细胞诱导免疫耐受的机制。
Conclusion The key to success of setting up rats model of heterotopic heart transplantation is that:(1)Appropriate anaesthetization depth;
结论手术成功的关键:(1)合适的麻醉剂量和深度;
Conclusion The key to success of setting up rats model of heterotopic heart transplantation is that:(1)Appropriate anaesthetization depth;
结论手术成功的关键:(1)合适的麻醉剂量和深度;
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