• Objective:To probe into the mechanism of Shenshuai Capsule in delaying advance of chronic renal failure(CRF)and against interstitial renal fibrosis.

    目的探讨胶囊延缓慢性肾功能衰竭CRF)进展及抗肾间质纤维化机理

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  • In Belgium, at least 70 people required renal transplants or dialysis for interstitial fibrosis of the kidney after taking the wrong herb from the Aristolochiaceae family, again as a dietary aid.

    比利时至少有70个人在不正确地采用马兜草药作为助食品而需要移植间质纤维化而做透析

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  • Objective To observe the protective effect of Biejiajian Pills on experimental rat kidney from renal interstitial fibrosis and discuss the mechanism.

    目的观察鳖甲煎间质纤维化实验大鼠肾脏保护作用探讨作用机理。

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  • The imbalance of interstitial cell proliferation and apoptosis and the metabolic disorder of intercellular substance, are two essential factors for renal tubulointerstitial fibrosis.

    细胞增殖凋亡失衡细胞间代谢失调也是造成小管间质纤维化两个不可缺少原因

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  • Renal interstitial fibrosis is the common pathological procedure to renal function failure of many kinds of renal diseases.

    间质纤维化多种肾脏疾病走向肾功能衰竭共同病理过程

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  • Conclusion Tetrandrine, tetramethylpyrazine and amygdalin may play important roles in prevention and reversion of renal interstitial fibrosis.

    结论汉防己甲素川芎嗪苦杏仁甙预防逆转间质纤维化中起重要作用

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  • Objective To study the protective effects of Shenyankangfu tablet on renal interstitial fibrosis in rats with unilateral ureteral obstruction (UUO).

    目的研究肾炎康复片对单侧输尿管梗阻(uuo)间质纤维化保护作用

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  • Renal interstitial fibrosis; Renal tubular epithelial cell; Mitochondria oxidative damage; Renal tubular function.

    间质纤维化;肾小上皮细胞线粒体氧化损伤;肾小管功能

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  • Objective To investigate the expression of P21 in renal interstitial fibrosis rats and the effect of enalapril on it.

    目的:动态观察P 21单侧输尿管梗阻纤维化大鼠模型中的表达,以及依那普利表达的调节。

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  • All the rats were sacrificed in 9 days, the kidneys were collected, and renal interstitial fibrosis was examined by PAS staining.

    术后9处死各组鼠,组织标本PAS染色确证纤维化病变

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  • OBJECTIVE: the renal interstitial fibrosis (RIF) is almost the common pathway by which all the various chronic kidney diseases (CKD) progress to end stage renal disease (ESRD).

    目的间质纤维化(RIF)各种不同病因慢性肾脏病(CKD)随着病程进展进入终末期肾病(ESRD)的一个进行性、不可逆的共同途径

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  • The renal interstitial cells increased in rats of the model group with the basal membrane thickened and shrank as well as obvious fibrosis, which were aggravated with the time prolonging.

    模型大鼠管间质细胞增多,肾小管基底皱缩纤维化明显,随时间进展加重

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  • Conclusions1. Mineralocorticoid inhibition can prevent chronic renal interstitial fibrosis caused by AA.

    结论1、抑制AA所致慢性间质纤维化有一定的防治作用。

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  • P21 may participate in the pathogenesis of renal tubule-interstitial fibrosis.

    P21可能参与小管间质纤维化发病过程。

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  • Objective: renal interstitial fibrosis is the common way to final renal failure. Renal interstitial fibrosis play more dangerous role than glomerulosclerosis in the kidney.

    目的纤维化多种肾脏疾病进展至终末期肾衰竭共同通路

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  • For example, ED5 reduces cortical Egr-1 mRNA expression and interstitial fibrosis in rats 7 days after renal obstruction (unilateral ureteral ligation) and delivery by electroporation.

    例如ED5可以减少小鼠尿路梗阻单侧输尿管结扎通过电穿孔法切除肾脏7天后皮质早期生长反应基因-1信使RNA表达间质纤维化

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  • Connective tissue growth factor (CTGF) is generally considered has an important role in this pathological process, for the treatment of renal interstitial fibrosis research to provide new ideas.

    普遍认为结缔组织生长因子(CTGF)病理过程中有着相当重要作用,将研究治疗间质纤维化提供新的思路

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  • The experiments on animal models are necessary for studying renal interstitial fibrosis. Researchers should find right animal models according to different objectives.

    动物模型实验研究纤维化必不可少的手段,实验者根据不同的实验目的选择适当的动物模型。

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  • The progression of decrease in expression of VDR indicates VDR may relate to renal interstitial fibrosis.

    VDR表达进行性减少提示其与间质纤维化有关。

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  • Conclusions activin a can promote the proliferation and transdifferentiation of renal tubule cells, which suggests that activin a may play an important role in interstitial fibrosis of renal tubule.

    结论激活a促进小管上皮细胞增殖转分化提示激活素a可能肾小管间质纤维化重要作用

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  • Immunologic disease can also complicate solid organ transplantation. Here is a renal biopsy that demonstrates marked interstitial fibrosis in a patient with chronic vascular rejection.

    免疫疾病往往使实质脏器移植变得复杂。图示慢性血管排斥病人活检见间质纤维化

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  • Objective: To study the effects of "Kangxian Ling Decoction" (KLD) on renal interstitial fibrosis induced by unilateral ureteral obstruction (UUO) in rats.

    目的探讨中药抗纤大鼠单侧输尿管结扎(UUO)所致纤维化的防治作用及机制。

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  • Objective: To study the effects of "Kangxian Ling Decoction" (KLD) on renal interstitial fibrosis induced by unilateral ureteral obstruction (UUO) in rats.

    目的探讨中药抗纤大鼠单侧输尿管结扎(UUO)所致纤维化的防治作用及机制。

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