2,5- and 2,6-disubstituted benzazole analogues are used as protein kinase inhibitors.
2,5和2,6双取代氮茚类似物被用作蛋白激酶抑制剂。
Cyclic AMP binds to the regulatory subunit of protein kinase A: Protein kinase A phosphorylates phosphorylase kinase.
环腺苷酸结合蛋白激酶的调节亚基:一个磷酸化蛋白激酶磷酸化酶激酶。
Thymidine kinase gene is found in herpes simplex virus.
胸苷激酶基因被发现在单纯疱疹病毒。
Kinase Buffer can be used to assay protein kinase activity.
激酶缓冲液用来分析蛋白激酶的活性。
The kinetic property of glycerol kinase from debaryomyces sp.
甘油激酶基本动力学性质研究。
Is PDGF tyrosine kinase inhibitor effective in pancreatic cancer?
PDGF受体酪氨酸激酶抑制剂在胰腺癌中是否有作用? ?
Overall, the results from oral kinase inhibitors are very exciting, says Robinson.
整体而言,口服激酶抑制剂的结果已经非常令人兴奋了,罗宾逊说。
In the past we relied on creatine kinase or the MB fragment of creatine kinase.
过去我们依靠肌酸激酶或肌酸激酶MB片段进行诊断。
Objective: to study the expression of mitochondrial creatine kinase in lung cancers.
目的:研究线粒体肌酸激酶在肺癌中的表达及意义。
Objective: to review the progress in the research of tyrosine kinase inhibitors in recent years.
目的:对近年来酪氨酸激酶抑制剂的研究进展作以综述。
The latter encodes a novel protein kinase with LIM domains and is strongly expressed in the brain.
后者以LIM范围编码了一个新奇的蛋白质激酶,并且在大脑中强烈地表达。
It binds and activates protein kinase c, causing a wide range of effects in cells and tissues (1, 2).
它结合并激活蛋白激酶c,对很多细胞和组织产生影响(1,2)。
Insulin receptor substrate 2 (IRS-2) is one of the major substrates of the insulin receptor kinase (1).
胰岛素受体底物2 (IRS - 2)是胰岛素受体激酶的主要底物之一(1)。
For example, a group of drugs called kinase inhibitors block the signals involved in blood vessel growth.
例如,一组叫做磷酸抑制剂(kinase inhibitors)的药物可以阻断血管增生的信号。
But ERBB3 is a pseudo-kinase; it functions only by binding with other proteins that have kinase activity.
但ERBB3是一种假激酶,它仅通过与其他有激酶活动的蛋白相互作用才能发挥功能。
The scientists successfully identified the small enzyme molecule responsible, a gene called focal adhesion kinase.
科学家成功分离出这种小小的酶分子,基因学上称之为局部粘着激酶。
Conclusion Genistein and daidzein were two effective inhibitors of recombinant human protein kinase CK2 in vitro.
结论染料木黄酮和大豆甙元是两种有效的重组人CK2全酶的抑制剂。
The extracellular signal-regulated kinase(ERK) is an important member of mitogen-activated protein kinase(MAPK) family.
细胞外信号调节激酶是丝裂原激活蛋白激酶家族的重要成员。
Stimulation of this receptor in vitro results in up-regulation of activated extracellular signal–regulated kinase (ERK).
体外实验中对相应受体进行刺激后导致对细胞外信号调节酶(ERK)的激活有促进作用。
Novel Oncogene with Kinase-domain (NOK) is a novel tumor-related gene, coding receptor like protein with a kinase domain.
是一个新的肿瘤相关基因,其结构上与受体蛋白相似,具有一个蛋白激酶结构域。
The drugs work by preventing an enzyme called tyrosine kinase from launching a signaling cascade that fuels tumor cell growth.
这些药物的作用机制是阻断酪氨酸激酶启动信号级联反应,后者可以促进肿瘤细胞生长。
Being deprived of even one essential amino acid is enough for the GCN2 kinase to switch the metabolism into an emergency mode.
即使是去除一种必需氨基酸也足够让GCN2激酶把代谢调到紧急模式。
Objective to investigate the correlation between phosphatidylinositol 3 kinase (PI3-kinase) and the pathogenesis of psoriasis.
目的探讨磷脂酰肌醇3激酶(PI 3激酶)与银屑病发病的相关性。
Products of viral oncogenes, most commonly retroviral oncogenes. They usually have transforming and often protein kinase activities.
病毒癌基因最常为逆转录病毒致癌基因的产物。通常具有转化和蛋白激酶活性。
KIT protein is expressed in SCLC, and its kinase activity has been implicated in the pathophysiology of many tumours, including SCLC.
KIT蛋白在小细胞肺癌中表达,它的激酶活性与许多肿瘤的病理生理学都有联系,包括小细胞肺癌。
In contrast, the mice without the GCN2 kinase kept a steady liver mass and lost only 69 percent of the adipose tissue on their abdomens.
相反,没有GCN2激酶的小鼠没有肝重量减少,只有69%的腹部脂肪组织减少。
In many inflammatory diseases such as septic shock (9), and psoriasis (10) the change in protein tyrosine kinase activity has been shown.
在许多炎症性疾病,如感染性休克(9),与银屑病(10),酪氨酸蛋白激酶的活动会表现出变化。
Mutations in GNA11 induced spontaneously metastasizing tumors in a mouse model and activated the mitogen-activated protein kinase pathway.
在小鼠模型中,GNA11突变诱导了自发转移性肿瘤,激活了丝裂原活化蛋白激酶途径。
Mutations in GNA11 induced spontaneously metastasizing tumors in a mouse model and activated the mitogen-activated protein kinase pathway.
在小鼠模型中,GNA11突变诱导了自发转移性肿瘤,激活了丝裂原活化蛋白激酶途径。
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