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- So that brings us back to -- it's a feature that will be disabled by tonight, I'm sure.
所以那个带我们回到-,这个特征在今天晚上会被关闭，我确定。
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This is the Renaissance Hotel. And it was closed for 80 years,
这是万丽酒店。它已经关闭八十年了，
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There is a blunting in this activation, and this blunting is correlated with this schizophrenic self-reported lack of desire negative symptorms.
这部分的活动被关闭了，而这种关闭活动的结果和精神分裂症患者,缺少欲望症状的报告相符。
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you could characterize them in terms of how they're gated, -- and basically how they open or close -- that's one way to talk about different types.
你可以通过闸门的类型来描述它们，这基本上也就是看它们是如何打开或关闭的-,这是一种讨论不同类型的方法。
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Kinases can, in many cases, serve as a mechanism for switching a protein on or switching a protein off.
激酶能够,在很多情况下,能够激活一种蛋白或者关闭一种蛋白
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So if you're curious this one I'm gonna kill off - because it will take a little while-- you'll find that available on the cloud if you'd like to experiment whether or not you're doing that edition or the other.
由于时间关系，我就现将其关闭,如果大家觉得好奇-,可以自己尝试一下,不管你是否选择将这个版本作为,实验内容。
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It makes no sense to think that it could try to kill the people who are trying to shut it down and so forth."
它会有试图杀死要将程序关闭的人等其他举动,这些完全说不通
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All cell phones off and we will begin.
请大家关闭手机,我们要开始了
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Imagine I have a little lamp, a little goose- one of those little gooseneck lamps, I'd put it on the table here, I'd put the height about a f-- about a foot off the table. And if I was really good, - I could hit, or time it so that when I hurt- yeah, try again. When I turn this on switch on in the lamp, at exactly the same time, I'm going to hit a key on my computer and start it running.
想象下我有一个那种小雁颈台灯-,我把它放在桌子上，大概离桌子，有一英尺那么高吧,这样挺好的，我可以打开-,或者关闭这灯,并在这同时，我可以让我电脑,开始运行。
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and ideally at some point coal, coal-fire power plants.
理想情况下，在某个时间点可能还会关闭煤炭以及燃煤电厂。
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Peter wields the keys of the kingdom of heaven and can open and shut the doors of personal salvation, just as he can open and shut the doors of the church.
彼得挥舞着通往天堂极乐的钥匙,他可以任意打开关闭，凡人可借此得救的大门，正如他可以任意操控通往教会的大门一样。
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For some reason they shut down their Columbia bookstore, but they've opened up now in Princeton.
但因为某些原因,他们关闭了,哥伦比亚大学那家店,但他们现在在普林斯顿又新开了一家
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So, for example, if we look at sodium channels, and sodium channels are some of the particularly prevalent ones when we're talking about neurons, if you think about the cell membrane, and this little green cartoon is me trying to show a sodium channel here, and in this case, you can see that it's closed, such that no ions are getting through.
比如，让我们来看一下钠离子通道，钠离子通道是我们会经常遇到的几个之一,在讨论神经元的时候，如果大家想想细胞膜，而这个绿色的小示意图就是我用来表示,钠离子通道的，在这种情况下，大家可以看到它是关闭的，因此没有离子可以通过。
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The memory bank, in turn, activates the electronic circuits; the window closes, the door opens, hopefully the cat comes in, and the automatic telephone goes into action; right?
内存条，轮流地，激活电子电路，关闭窗子，打开门，希望猫进来，自动电话开始行动，对不？
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It has a gate on it and that gate is in open or close state depending on whether a ligand is present or not.
在这个通道上有个门,这个门是打开还是关闭,取决于配体到来与否
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That's shown functionally here but recovery means that this sodium channel becomes closed again.
在此展示了这项功能,恢复代表着钠离子通道再次关闭
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You don't need a light switch or a light bulb or an iPhone app to turn something on or off.
你不需要一个电灯开关,或者一个电管,或者打开关闭一个iPhone应用程序。
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Now, remember we talked about these last time, voltage-gated channels are channels that would allow the passage of sodium, in this case, but they can exist in two states, a closed state and an open state.
还记得我们上节课讨论过的吧,电压门控通道是,一种可以容许钠离子通过的通道,在这一例子中 电压门控通道有两种状态,关闭状态和开放状态
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Some proteins can be switched from an 'off' position where they don't do anything to an 'on' position where they now do something by only a chemical reaction like this where a phosphorous is added.
一些蛋白质可以从关闭状态的,无所作为,到成为开启状态后,执行某种功能,中间只发生了一个引入磷酸基的化学反应
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I couldn't have told you, for example, if we look at a phosphate group, that that's going to be incredibly important in DNA, that it's also an incredibly important group when you're dealing with proteins and whether you're turning the function of a protein on or off.
怎么和化学反应相联系起来的，更不记得其它我更不感兴趣的规律,我不能告诉你，如果我们看磷酸盐,它们对于构成DNA十分重要,也是构成蛋白质的重要组份,它是否能打开或关闭一个蛋白质的功能。
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and getting rid of natural gas plants, for instance,
同时关闭天然气工厂等等，
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And we will close sectioning by this Friday at the time to be stated on the course's website.
这周五我们会,关闭网站上的部分章节。
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The heater is on, it's producing heat until a negative signal is registered, 'oh we've gone too high', and then it turns off.
加热器会开着,一直产生热量直到它得到一个关闭的信号,噢我们弄得太热了,然后就关闭了
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And Hal says, as Dave begins to shut down Hal's circuits, "I'm afraid. I'm afraid, Dave."
当戴夫开始关闭它的电路时,哈尔说,我害怕,我害怕,戴夫
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If a ligand comes and interacts with a receptor, it opens up; In the presence of this ligand, if the ligand goes away, it closes.
如果配体与受体相互作用,在配体存在的情况下通道打开,如果配体脱离,通道就关闭
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People remembered that during World War II the U.S. Government shut down the housing market.
大家应该还记得,二战期间,美国政府关闭了房地产市场
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And proceeds to do the only thing he can do to defend himself against Hal, which is shut down the program, basically killing-- if we can talk that way--killing Hal.
而他唯一,能使让哈尔不伤害到自己的举措,就是关闭该程序,基本上也就是杀死,如果我们可以那样表达的话,杀死哈尔
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It turns out that it didn't turn into World War III and -maybe they did shut down the housing or they must have curtailed it, but it created that boom.
结果没有爆发第三次世界大战,也许政府真的关闭了房产市场,至少他们限制了房地产,而这促进了房地产繁荣
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Most companies do splits because that might close the-- you might have been thinking about investing in Google but you could still--you could just say, I want to buy ten shares or five shares and the broker will do it for you, but they might charge a higher commission.
大部分公司会分割,因为这样会关闭...,比如你想投资谷歌,但是你可以说,我想买十股,或者五股,经纪人会照办,但是会索取更高的佣金
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In the other context, you know in a Window and a Windows machine, you close it with the X on the top right hand corner, where do you close it in the Mac?
还有一个就是，在Windows操作系统下,当你要关闭某个东西时，需要点击,右上角的“X“,那在Mac操作系统下呢？
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