I don't know why they make such a big deal out of the person landing on the moon.

我不理解人类登月,有什么大不了的。

哈佛公开课 - 幸福课课程节选

But some ways you could ask, who cares? What does it matter?

但同时有些人会说,管它呢,这又有什么大不了的呢

耶鲁公开课 - 关于食物的心理学、生物学和政治学课程节选

What's the great oddity about the keyboard?

键盘有什么大不了的

耶鲁公开课 - 聆听音乐课程节选