Most cells in your body have insulin receptors so insulin is starting to bind to insulin receptors on those cells.

体内大多数细胞中都有胰岛素受体,胰岛素就开始与细胞上的胰岛素受体结合

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What insulin is doing inside your body is acting as a ligand for insulin receptors which stimulate certain kinds of cellular responses.

胰岛素在体内的功能就是作为,胰岛素受体的配体,刺激产生某种细胞效应

耶鲁公开课 - 生物医学工程探索课程节选

So, it interacts with receptors called insulin receptors that are on cells that are sensitive to insulin.

它与细胞表面胰岛素受体相互作用,这些细胞对胰岛素很敏感

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We've identified many drugs that stimulate insulin receptors, for example, but they're not exactly insulin, and those can potentially be used as agonist type drugs.

我们已经设计了很多,能够激活胰岛素受体的药物,但它们都不是和胰岛素分毫不差的,但都可以用作激动剂类药物

耶鲁公开课 - 生物医学工程探索课程节选

It gets enhanced because when insulin binds to the insulin receptor, it activates the receptor.

这种增强效应来自于,胰岛素与胰岛素受体结合后,就激活了该受体

耶鲁公开课 - 生物医学工程探索课程节选

Insulin binding leads to phosphorylation, leads to other biochemical changes.

胰岛素与受体结合导致磷酸化,进而产生其它生物化学变化

耶鲁公开课 - 生物医学工程探索课程节选

Insulin, the ligand binds to its receptor, creates a change through a kinase activity that's exposed, which leads to other biochemical changes, which leads to a change in cell behavior - in this case the cell behavior is that more glucose transporters are brought to the membrane and more glucose can enter the cell.

胰岛素,一种能够与受体结合的配体,通过其暴露出的激酶活性引起的变化,导致了其它后续生化变化的发生,进而使细胞行为发生改变,这个例子中的细胞行为就是,更多的糖载体被带到细胞膜表面,这样更多的糖分子进入到细胞内部

耶鲁公开课 - 生物医学工程探索课程节选