Despite that disadvantage, the United States won and maintained a 53-game winning streak at home against regional opponents that started in 2001, when they lost to Honduras.

VOA: standard.2009.06.07

One of the concerns out of the gate for students in this course, particularly those we dub less comfortable is that you're already starting off at a disadvantage.

另外一个比较关心的是,还没有入门的同学，尤其是那些有点跟不上的同学,你们的学习处于劣势。

哈佛公开课 - 计算机科学课程节选