This much scientists knew. However,they were not clear on how that receptor was activated when this kind of painful event occurred.

VOA: standard.2010.05.04

some with the capsaicin-receptor and some that had been genetically modified to eliminate that receptor.

VOA: standard.2010.05.04

"The ability of these substances to activate pain neurons was totally dependent upon capsaicin receptor."

VOA: standard.2010.05.04

It really produces its effects primarily by just activating the so-called capsaicin receptor."

VOA: standard.2010.05.04

Another would soak it up, before it reached the receptor on the neuron.

VOA: standard.2010.05.04

When you touch boiling water, for example,get a cut, or even exercise too much, a special receptor on the neuron is activated, sending a signal to the brain - that hurts!.

VOA: standard.2010.05.04