The antigen has to be presented to helper T-cells, those helper T-cells have to stimulate a B-cell population to both proliferate and differentiate.

抗原需要被呈递给辅助性T细胞,这些辅助性T细胞需要激活B淋巴细胞,使其增殖和分化

耶鲁公开课 - 生物医学工程探索课程节选

That's shown here, a B-cell gets stimulated, matures into an antibody producing factory.

这里展示的是,当一个B细胞被激活,分化成熟为一个生成抗体的工厂

耶鲁公开课 - 生物医学工程探索课程节选