The researchers knew it would be easier and less costly to map a smaller frog with fewer chromosomal pairs.

VOA: special.2010.06.29

Has only half of the diploid chromosomal content that most of the cells, which are called somatic cells in our body have.

卵子中只含有我们机体一半的染色体,二倍体基因组中一半的染色体,这些二倍体细胞称为体细胞

耶鲁公开课 - 生物医学工程探索课程节选

They're not chromosomal differences because this is the ordinary process of mitosis.

它们的染色体没有任何变化,因为这是正常的有丝分裂过程

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You put this chromosomal DNA or this DNA that you're interested in, double stranded into a test tube.

你把这个染色体DNA,或者你感兴趣的双链的DNA,放进一个试管

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How could I identify in a chromosomal DNA sample whether the sickle gene is present?

那我该怎么确定某染色体DNA样本中,是否存在这种致病基因呢

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If I took this same restriction enzyme and tried to cut the chromosomal DNA of a sickle patient, it wouldn't cut at that point because the wrong sequence is there.

而如果我用同样的限制酶,去切割病人的染色体DNA,那该酶是不会起作用的,因为基因序列不对

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Well I talked about it - earlier I've mentioned several times all the cells in my body, all the cells in your body have essentially the same genomic chromosomal DNA in their nucleus.

我之前有说过,我不只一次提到过,我体内的所有细胞,和你体内的所有细胞一样,核中的染色体基因组DNA本质上都相同

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One way I could try to find the gene for human insulin is to take any cells from any of us, skin cells let's say, and I could identify where on the chromosomal DNA that insulin is likely to occur.

我能找到胰岛素基因的一个方法,是从任意一个人身上任意取一些细胞,比如说皮肤细胞,并且我知道胰岛素基因,可能出现在染色体DNA的哪一部分

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We're going to take a chromosomal DNA, we're going to digest it with this restriction enzyme, we're going to put it in this tube and run it on a gel, and we're going to see what results down here.

我们取一条染色体DNA,然后用限制酶进行分解,接着再放,在凝胶上进行电泳,之后看看结果如何

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