U.N.aid agencies describe a chaotic scene of misery and desperation.

VOA: standard.2009.08.21

But humans continue their violent and evil ways, And in desperation, God wipes them out, and starts again.

但人类继续他们暴力邪恶的行径，绝望时，上帝将他们消灭，重新开始。

耶鲁公开课 - 旧约导论课程节选

I want to show people's desperation

我想展现人们的绝望，

肉品市场区的作家 - SpeakingMax英语口语达人

My belief in books had risen more out of a sense of desperation than from my abiding conviction of their ultimate value.

我对书的信仰更多的是来自一种绝望,而非我对其本质的长期依赖，“

耶鲁公开课 - 1945年后的美国小说课程节选

Again,getting rid of the negative does not guarantee us the positive, which is why already in the 1940s, wrote that most men lead lives of quiet desperation.

再强调一次，摆脱消极,不能保证我们变得积极，因此早在19世纪40年代，认为，大多数人都活在沉默的压抑中。

哈佛公开课 - 幸福课课程节选

? How can we get beyond that "quiet desperation"?

要怎样摆脱“沉默的压抑？

哈佛公开课 - 幸福课课程节选

Dante He mentions Virgil and Dante, and it seems like the desperation of bringing up such grand figures makes me think that he does have doubts.

他提到了Virgil和，提到的那些伟大的人物时他的绝望,让我觉得他也心存疑惑。

耶鲁公开课 - 1945年后的美国小说课程节选