Word expert James Rogers says the word "it" in the saying can mean any and all difficulties.

VOA: special.2010.11.21

A lot of sciences rest on data that is flawed in some ways because of the difficulties in assessing what people eat.

许多依赖数据的科学常识是有瑕疵的,由于评估人类所吃食物非常困难

耶鲁公开课 - 关于食物的心理学、生物学和政治学课程节选

I think that would help solve a lot of the medical difficulties that people have these days.

我认为这种办法可以帮助解决现在困扰人们的许多医学难题。

生物克隆是热点问题 - SpeakingMax英语口语达人

He talked about personal responsibility, and used himself as an example of someone who overcame difficulties.

VOA: special.2009.09.10

Okay, so you could see difficulties in estimating on both sides of the norm. Yes?

所以你们可以看到在一定范围内,做估算有多困难

耶鲁公开课 - 关于食物的心理学、生物学和政治学课程节选

Her main goal was to increase public interest in the difficulties of people with physical problems.

VOA: special.2009.11.15

instead of pursuing the questions of how exactly that theory should go, notice that if we had that theory ... we could still evaluate in principle-- whatever the practical difficulties might be-- in principle we could still evaluate rival lives.

我们不去研究,那种理论如何发挥作用，即便我们有那种理论,原则上我们仍然可以-,不管实际困难是什么-,原则上我们仍然可以评价其他生活。

耶鲁公开课 - 死亡课程节选

Miz McClellan praised Wilma Mankiller's ability to lead and help others during such personal difficulties.

VOA: special.2010.04.09

the way we see,the way we experience the world, enlarge the capacity of the form and that's we are better able to deal the inevitable difficulties.

我们看待和体验世界的方式，让我们突破框架，引发潜能,使我们能更好地应对不可避免的困难。

哈佛公开课 - 幸福课课程节选

Officials believe that language difficulties cause problems for many in the Hispanic community.

VOA: special.2010.05.07

But, as I mentioned briefly in the last class, the notorious difficulties attending this poem seem to have very little to do with Milton's grief over the death of Edward King, which may well not have been all that troubled or complicated.

不过，正如我上节课简要提到的,这首诗的阅读障碍和弥尔顿对爱德华金之死的,悲啜之情并无太大关系，他的哀悼也不是使这首诗艰深复杂的全部原因。

耶鲁公开课 - 弥尔顿课程节选

Loneliness has been linked to health problems like depression and sleeping difficulties.

VOA: special.2009.12.22

Can you tell us about any difficulties you had when starting your own business?

你能给我们讲讲你创业过程中经历的困难吗？

关于创业的全部 - SpeakingMax英语口语达人

These difficulties place Poe's writing outside the main body of American literature.

VOA: special.2010.10.31

Do you have any difficulties in studying as a grad student?

你做为一个研究生学习有困难吗？

苦中有乐的学习 - SpeakingMax英语口语达人

Their success showed how people can conquer great difficulties.

VOA: special.2009.11.15

As I see it, there is only one solution to all the foregoing difficulties.

在我看来，解决这种困境只有一个办法。

耶鲁公开课 - 文学理论导论课程节选

A friend of Webster's described the meeting in these words: "Mister Clay came to Mister Webster's house and had a long talk with him about the best way to settle the difficulties growing out of slavery and the new territories.

VOA: special.2009.03.26

The Wall Street Journal is the most influential financial publication in this country but it has been going through financial difficulties with the Internet age.

华尔街日报》是我国最有影响力的,金融出版物,但是它在网络时代,遇到了财政危机

耶鲁公开课 - 金融市场课程节选

Sytev is a newlywed. He says leaving his wife is just one of the difficulties he's preparing for.

VOA: standard.2010.06.02

That's almost saying there are difficulties, and you didn't treat them either.

那等同于在说存在这些困难，只是没有去处理而已。

麻省理工公开课 - 固态化学导论课程节选

But the focus was on the secret military documents leaked by the Internet website WikiLeaks that highlighted the military difficulties in Afghanistan.

VOA: standard.2010.07.30

Do you have any difficulties in being close with them?

你跟他们的关系变得亲密有困难吗？

有趣的留学生活 - SpeakingMax英语口语达人

"Another possible scenario is that this fragile Shi'ite alliance will simply fall apart over the difficulties of nominating a consensus prime minister."

VOA: standard.2010.05.10

Have you met any difficulties in taking the tests?

你在考试中遇到过什么困难吗？

想学习宗教学 - SpeakingMax英语口语达人

Hearst says that he and Gluckstern encounter the same difficulties all entrepreneurs face, but once or twice their youth created a small issue.

VOA: standard.2010.01.31

Do you have any difficulties in teaching students?

在教学过程中，你遇到过什么困难吗？

布朗克斯的足球教练 - SpeakingMax英语口语达人

Given the difficulties ahead, the World Health Assembly approved a resolution to eradicate measles worldwide, but set no target date for achieving this goal.

VOA: standard.2010.05.21

And he modifies them or revises them or introduces new positions to deal with some of the difficulties that he was setting himself to be open to earlier.

他会调整,修改那些观点,或者以引入新观点,来解决先前他遇到的难题

耶鲁公开课 - 死亡课程节选

It is also important to put these resources in places that help us cultivate capacity, the capacity to deal with these difficulties and hardships when they arise and they will arise.

同样重要的是，投入资源,帮助我们培养自身能力，应对困难和艰辛的能力,这些困难一直存在并会继续出现的。

哈佛公开课 - 幸福课课程节选