• The DNA molecule here has been spread apart, opening up two single stranded DNA's which have complementary base sequences because they were double stranded DNA.

    这里DNA分子被分开,形成两条单链DNA,这两条单链碱基序列互补,因为它们是由双链DNA解旋形成的

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  • It has to do with the nature of this complementary binding between double stranded DNA and the fidelity of this base pair matching in forming stable DNA molecules.

    这些特性能从根本上解释,为何DNA双链的碱基能互补配对,以及在形成稳定的DNA分子结构时,碱基互补配对为何具有一致性

    耶鲁公开课 - 生物医学工程探索课程节选

  • If I'm talking about two DNA strands and they differ only in one or two base pairs they won't be exact complements and they won't form this double helix.

    假设有两条DNA单链,有一两个碱基不能配对,它们就不能完全互补,也无法形成双螺旋形结构

    耶鲁公开课 - 生物医学工程探索课程节选

  • The native structure is this double stranded structure here and if I heat it up slightly and I add some base, so under slightly basic conditions, these molecules will fall apart because you've created conditions where the hydrogen bonding is no longer favorable so they peel apart.

    原始结构,在这里就是指DNA双链,如果我稍微加热,并且加入一些碱,在弱碱性的条件下,这些配对碱基会分开,这是因为在一定条件下,碱基对之间的氢键,不再稳定并且会断裂分开

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  • Now DNA is a double helix and I've only shown you one part of the helix, right? I've shown you one upright strut and a base hanging off of it, but it forms a double helix because complementary strands of DNA strongly associate with one another and that's a very stable structure.

    NA是双螺旋,我只是给你们讲了螺旋的一边,我给你们演示,一条链的支柱及碱基团,但其能构成双螺旋,是因为DNA是完全互补的两条链,彼此之间结合紧密,结构异常稳定

    耶鲁公开课 - 生物医学工程探索课程节选

  • If I had a beaker sitting on the table here and it contained a million blue double stranded DNA molecules and a million red double stranded DNA molecules and I heated it up and added a little base, I'd soon have four million individual strands just floating around in the solution because I've broken up this hydrogen bonding and the DNA molecules fall apart.

    假如我这里有一个烧杯 里面,盛有一百万条蓝色DNA双链和,一百万条红色DNA双链,然后我稍微加热一下烧杯,并且加一些碱,很快我就有了四百万条DNA单链,漂浮在溶液里,因为我已经使得氢键断裂,DNA双链也随之打开

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