One thing to notice is this part of the double helix that we'll call the backbone.

要注意的是,这两股构成双螺旋的链我们称之为主链

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Those are two continuous strands that wind around each other to form the double helix.

这两股主链,相互缠绕形成双螺旋

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I want to start by showing you this cartoon that you already know about with the structure of a double helix.

我想要给你们看这张卡通模型,你们都知道,这是DNA双螺旋结构

耶鲁公开课 - 生物医学工程探索课程节选

Hybridization simply means that DNA will re-nature and form a stable double helix only with its particular match, only with the hybrid that it is perfectly complementary, too.

核酸分子杂交表示,DNA在变性状态下可以恢复活性,和与其配对的单链形成稳定的双螺旋结构,只有在完全配对时才会发生这种情况

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DNA is a double helix, you know this, the double helix was--the structure of DNA was discovered about the time that I was born you've always lived with it.

NA是双螺旋结构,众所周知,DNA的这种双螺旋结构,是在我出生的那个年代才被发现的,它就是你生命的一部分

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If I'm talking about two DNA strands and they differ only in one or two base pairs they won't be exact complements and they won't form this double helix.

假设有两条DNA单链,有一两个碱基不能配对,它们就不能完全互补,也无法形成双螺旋形结构

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Now remember that there were only four different colors in the cartoon of the DNA double helix that we talked about and I told you that those colors are really - represent the bases but there's five of them here.

现在要记住只有四种不同的颜色,在双螺旋DNA的卡通模型上出现,我们刚说过这个,我告诉你们的这些颜色,它们代表不同的碱基,不过有五种碱基

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Now DNA is a double helix and I've only shown you one part of the helix, right? I've shown you one upright strut and a base hanging off of it, but it forms a double helix because complementary strands of DNA strongly associate with one another and that's a very stable structure.

NA是双螺旋,我只是给你们讲了螺旋的一边,我给你们演示,一条链的支柱及碱基团,但其能构成双螺旋,是因为DNA是完全互补的两条链,彼此之间结合紧密,结构异常稳定

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