Doctor Chan says the effects appeared especially strong among patients with tumors expressing an enzyme called COX-2.

VOA: special.2009.09.01

So now, the enzyme is locked up with being built, and the penicillin has effectively killed the bacteria.

所以这是我第一次感受到,我想在单个原子的层面上思考这些分子,所以这时我的专业转到了化学方向。

麻省理工公开课 - 化学原理课程节选

So, she is interested in how this molecule, gemcitabine, inhibits an enzyme. So, to do those studies, she needs to know a lot of the stuff on this list.

她对这个分子，二氟脱氧胞嘧啶核苷怎么抑制酶很感兴趣，要做这些研究。

麻省理工公开课 - 化学原理课程节选

The Royal Swedish Academy of Sciences says it is honoring the researchers for showing how telomeres and the enzyme that makes them protect chromosomes.

VOA: special.2009.12.08

They often involve networks of reactions, not just one enzyme but a series of enzymes that serve to amplify each other.

这些反应通常包括一个反应网络,不只是一种酶,而是一系列的酶来进行级联放大

耶鲁公开课 - 生物医学工程探索课程节选

The researchers developed a mixture of chemicals that interfered with the performance of the enzyme.

VOA: special.2010.04.07

Or you could ask the question, I have this restriction enzyme, at what regions on this plasmid will it cut?

你也可以这样问,我的这种限制性内切酶,会从质粒的哪个区域切开呢

耶鲁公开课 - 生物医学工程探索课程节选

Some scientists are studying whether drugs that block the enzyme can help fight cancer.

VOA: special.2009.10.07

What a kinase enzyme does is that it recognizes this protein, and for example, the tyrosine that's on the protein.

激酶能够识别这类蛋白,例如,包含酪氨酸的蛋白

耶鲁公开课 - 生物医学工程探索课程节选

But,cell death is delayed if a lot of the enzyme telomerase is produced.

VOA: special.2009.10.07

She needs to know this enzyme works by both acid base chemistry, and oxidation reduction.

她要知道酶催化，她需要知道这种酶,在酸碱环境下的反应和氧化还原反应。

麻省理工公开课 - 化学原理课程节选

One form of this enzyme makes the prostaglandin that causes pain and swelling.

VOA: special.2010.12.14

Of course, she needs to know the basic principles, but she's also talking about it an enzyme, so she needs to know about enzyme catalysis.

她需要知道这表上的许多东西，当然她需要知道到这些基本原理，她研究的是一种酶。

麻省理工公开课 - 化学原理课程节选

Telomerase is the enzyme in the body that builds the telomeres.

VOA: special.2009.12.08

In this case, this particular restriction enzyme cuts symmetrically like this, but not at the same point.

在我们这种情况下,这个限制性内切酶总是这样对称地切割,但两条链切割的位点不一样

耶鲁公开课 - 生物医学工程探索课程节选

The weakness is an enzyme called N-myristoyl transferase,or NMT.

VOA: special.2010.04.07

This restriction enzyme was found in a natural source, it was found in a micro-organism called E.coli.

这个限制性内切酶源于自然界,是从名为大肠杆菌的微生物中发现的

耶鲁公开课 - 生物医学工程探索课程节选

Miz Blackburn and Carol Greider identified the enzyme telomerase.

VOA: special.2009.12.08

So, that's kinetics -- how fast a reaction will go, and from the perspective of someone who's a biochemist, I'm interested in kinetics and enzyme kinetics, and thinking about molecules that catalyze reactions in the body.

所以这就是动力学，一个反应发生的有多快,从一个生物化学家的角度,我喜欢研究动力学,酶动力学。

麻省理工公开课 - 化学原理课程节选

Another form of the enzyme creates a protective effect.

VOA: special.2009.10.20

So, these are receptors, for example, that bind the ligand and then liberate an enzyme which promotes some sort of reaction inside the cell, often it's kinases but doesn't have to be.

例如,这里是受体,与配体相结合,激活一种酶,这种酶能够催化细胞内的某些反应,这些酶通常都是激酶,但不全是

耶鲁公开课 - 生物医学工程探索课程节选

The scientists named the enzyme telomerase.

VOA: special.2009.10.07

A reaction performed by one enzyme creates a product that stimulates another enzyme that creates a product, and stimulates another enzyme, and through this cascade of reactions you amplify and carry the signal forward.

一种酶催化生成的产物会活化另一种酶,而它催化的产物又能激活其他酶,催化反应生成另一种产物,通过这层层反应,信号被放大,并不断向前传递

耶鲁公开课 - 生物医学工程探索课程节选

He says their research has identified an "Achilles' heel" of the parasite - an enzyme that is needed for the parasite's survival.

VOA: standard.2010.04.05

In some cells they're recycled, that is the cell is able to take up the neurotransmitter after it's released and restore it, but most often there are enzyme systems inside the pre-synaptic membrane where those neurotransmitters are synthesized.

在一些细胞中神经递质可以循环利用,这些细胞可以吸收,已经释放出的神经递质并重新储存起来,但更常见的是突触前膜中含有酶系统,在此合成神经递质

耶鲁公开课 - 生物医学工程探索课程节选

"The outer layers will slow down the penetration of digestive enzyme into the starch part so that the release of the sugar into the bloodstream will be slow for brown rice in comparison with white rice."

VOA: standard.2010.06.25

Another family is receptor tyrosine kinases, I'll show another picture in a moment that tells you more about what a kinase is, but a kinase is basically an enzyme that can add a phosphorous to another molecule.

另一类是酪氨酸激酶受体,马上我给你们看另一张图,这张图会更详细地告诉你们激酶是什么,激酶是一种能够,向其他分子上添加磷酸基团的酶

耶鲁公开课 - 生物医学工程探索课程节选

In this case, a receptor tyrosine kinase is a receptor molecule that binds a ligand at its surface outside the cell and initiates this enzyme activity - this kinase activity - and causes phosphorylation of another molecule.

在这个例子中,酪氨酸激酶受体可以,在细胞表面区域与配体结合,从而激发出,激酶的活性,使其能够磷酸化另一类分子

耶鲁公开课 - 生物医学工程探索课程节选

If that protein is an enzyme then you've and you've switched it from an 'off' position where it's not catalyzing a reaction to an 'on' position where it is, you've changed the biochemical state of the cell, you've changed the chemical reactions that can occur within the cell, and you've changed its behavior.

如果这种蛋白是一种酶的话,你就能够将酶从无催化作用的静息态,激活至能催化反应的激活态,你改变了细胞的生化状态,也改变了细胞内发生的化学反应,改变了细胞的行为

耶鲁公开课 - 生物医学工程探索课程节选

You first separated your DNA, let the primers bind, then turn on the enzyme, and it makes copies of each one of these.

首先解旋DNA双链,使引物结合,接着激活聚合酶,最终得到各链的复制产物

耶鲁公开课 - 生物医学工程探索课程节选