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They also have binding sites for antigen, but they are sort of two IgG type molecules bound together by another peptide chain.
同样IgA抗体表面也有与抗原结合位点,但它们就像两个IgG型分子,通过肽链相互连接
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On second exposure it's different, that IgG is produced predominantly on second exposure to an antigen.
而再次免疫则不同,再次接触相同的病原体时,人体主要产生的则是IgG
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So, many--the predominant number of antibodies in your blood look like these IgG molecules.
所以在你的血液中有许多抗体,看上去像IgG分子
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So, imagine taking two IgG's, turning one upside-down and then they're hooked together.
想象一下,有两个IgG分子,将其中一个倒置,那么两个分子将会相互钩住
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But not all of them do, there are different kinds of antibody molecules.
但是实际上并不全是IgG分子,这其中包含有很多不同种的抗体分子
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These are of the class called IgG, they're Y shaped molecules.
这种被称为IgG抗体,它们是Y形分子
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The IgM is really five IgG-type molecules that are linked together through disulfide bonds, such that their FC portions are all pointing in and their antibody binding portions are all pointing out.
gM是由五个IgG分子组成的,IgG分子之间通过二硫键连接,免疫球蛋白尾部的FC片段都指向内侧,而抗体的抗原结合位点都指向外侧
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The memory cells, which are stimulated, lead to an IgG response and that's why IgG is the antibody of-- that is produced predominantly after the boost, but there is some IgM produced also.
记忆细胞受到刺激之后,可以诱发分泌IgG的应答反应,这也是为什么IgG,是接种疫苗后产生的主要抗体,与此同时也刺激产生了一些IgM
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If you looked later, as the antibody production response matures, some IgG is produced so that in the late period after initial priming you'd have a mixture of IgM and IgG in the blood.
如果你稍后再观察,等到产生抗体的应答趋于成熟后,就会产生一些IgG抗体,在初次免疫的最终阶段,你的血液中有IgM,和IgG两种抗体
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Well, one way to think about is they have more antigen binding sites and so they're going to be more efficient at neutralizing the pathogen on a per-molecule basis than IgG is.
可以这么考虑,因为IgM表面有更多的抗原结合位点,所以相对于IgG,IgM在分子层面上,能够更为有效地与病原体结合
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Not only the IgG but there are special antibodies called secretory IgA and these are highly enriched in mucosal fluids in the mucus lining of your gut, and the eye, and of other--of mucosal organs.
不仅仅是IgG分子,还有一些特殊的抗体,被称作分泌型免疫球蛋白A,IgA在体内粘液中广泛存在,例如,在小肠内壁和眼球周围以及,其他带有粘膜的器官中都有IgA的分布
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