Word expert James Rogers says the word "it" in the saying can mean any and all difficulties.

VOA: special.2010.11.21

A lot of sciences rest on data that is flawed in some ways because of the difficulties in assessing what people eat.

许多依赖数据的科学常识是有瑕疵的,由于评估人类所吃食物非常困难

耶鲁公开课 - 关于食物的心理学、生物学和政治学课程节选

Do you have any difficulties in studying as a grad student?

你做为一个研究生学习有困难吗？

苦中有乐的学习 - SpeakingMax英语口语达人

Her main goal was to increase public interest in the difficulties of people with physical problems.

VOA: special.2009.11.15

Okay, so you could see difficulties in estimating on both sides of the norm. Yes?

所以你们可以看到在一定范围内,做估算有多困难

耶鲁公开课 - 关于食物的心理学、生物学和政治学课程节选

Officials believe that language difficulties cause problems for many in the Hispanic community.

VOA: special.2010.05.07

instead of pursuing the questions of how exactly that theory should go, notice that if we had that theory ... we could still evaluate in principle-- whatever the practical difficulties might be-- in principle we could still evaluate rival lives.

我们不去研究,那种理论如何发挥作用，即便我们有那种理论,原则上我们仍然可以-,不管实际困难是什么-,原则上我们仍然可以评价其他生活。

耶鲁公开课 - 死亡课程节选

But the focus was on the secret military documents leaked by the Internet website WikiLeaks that highlighted the military difficulties in Afghanistan.

VOA: standard.2010.07.30

The Wall Street Journal is the most influential financial publication in this country but it has been going through financial difficulties with the Internet age.

华尔街日报》是我国最有影响力的,金融出版物,但是它在网络时代,遇到了财政危机

耶鲁公开课 - 金融市场课程节选

He added that some stations experienced minor difficulties in operating the electronic registration rolls and party observers arrived at some polling stations without proper accreditation.

VOA: standard.2009.11.28

It is also important to put these resources in places that help us cultivate capacity, the capacity to deal with these difficulties and hardships when they arise and they will arise.

同样重要的是，投入资源,帮助我们培养自身能力，应对困难和艰辛的能力,这些困难一直存在并会继续出现的。

哈佛公开课 - 幸福课课程节选

But guess what? In the last decade weve been able to produce, in spite of all these difficulties, health workers in Mogadishu, in a hospital in Banadir University.

VOA: standard.2009.12.05

Do you have any difficulties in being close with them?

你跟他们的关系变得亲密有困难吗？

有趣的留学生活 - SpeakingMax英语口语达人

It's a much safer pill and a lot of the difficulties have been worked out in terms of safety and side effects, not all of them, but there are still problems with the Pill.

VOA: standard.2010.05.12

But, as I mentioned briefly in the last class, the notorious difficulties attending this poem seem to have very little to do with Milton's grief over the death of Edward King, which may well not have been all that troubled or complicated.

不过，正如我上节课简要提到的,这首诗的阅读障碍和弥尔顿对爱德华金之死的,悲啜之情并无太大关系，他的哀悼也不是使这首诗艰深复杂的全部原因。

耶鲁公开课 - 弥尔顿课程节选

The author acknowledges that after nine years of large-scale U.S.military involvement in the Middle East, and with the nation's economic difficulties bearing down on them, many Americans feel the temptation to pull the U.S.strong horse out of the region.

VOA: standard.2010.03.18

Have you met any difficulties in taking the tests?

你在考试中遇到过什么困难吗？

想学习宗教学 - SpeakingMax英语口语达人

This is presidential historian and author Robert Dallek: "Once the public turns against a war, once it is convinced that you are embarked upon if not a losing enterprise then something that is going to produce a quagmire, it creates tremendous political difficulties for the president and it undermines his credibility, trust in his judgment and his ability to put across his domestic reforms,"

VOA: standard.2009.10.09

Do you have any difficulties in teaching students?

在教学过程中，你遇到过什么困难吗？

布朗克斯的足球教练 - SpeakingMax英语口语达人

"What I would like for the country and everybody to know is that with the age of the computer, it takes time for us to try to keep up with the computer but if some people would start writing again, and sending their bills by mail, maybe it could ease a little of the burden as far as the financial difficulties that we are in."

VOA: standard.2010.04.13