But politics is (takes) a long, long time to make any significant, long-lasting difference."

VOA: special.2010.05.09

But finally,there was a significant difference on alcoholism, the number of people who became how many people were able to getting to do "the white collar" jobs.

酗酒方面两组有显著差异，酗酒人数有差异,成为白领的人数,两组有差异。

哈佛公开课 - 幸福课课程节选

Primarily the people who started are Emerson and Moscovici and many others who have done research showing how minority-- very often one person can make a big difference, can make a significant difference.

爱默生和莫斯科维奇是先驱,他们和其他学者都证明少数人-,经常是一个人，如何实现重大改变，能实现显著的改变。

哈佛公开课 - 幸福课课程节选

So, that's a very significant difference.

所以这是个很巨大的差异

耶鲁公开课 - 古希腊历史简介课程节选

And the significant difference between s orbitals and p orbitals that comes from the fact that we do have angular momentum here in these p orbitals, is that p orbital wave functions do, in fact, have theta and phi dependence.

轨道和ｐ轨道的,不同之处在于,在ｐ轨道，波函数，随theta和phi变化。

麻省理工公开课 - 化学原理课程节选