We've talked about one class of molecules, they're transporters that move molecules from inside to outside, or outside to in, that wouldn't ordinarily be transported through a cell membrane.

我们已经讲过一类这样的分子,它们是能够将分子从胞内运至胞外的载体,或者从胞外运至胞内,这个过程不是简单地穿过细胞膜

耶鲁公开课 - 生物医学工程探索课程节选

It could be that that signal is 'you need more glucose', and so the cellular response is to create more glucose transporters to bring more glucose into the cell.

这信号还可能是,"需要更多葡萄糖",细胞的反馈就是,产生更多的葡萄糖载体,将更多的糖分子输送进细胞

耶鲁公开课 - 生物医学工程探索课程节选

In order for it to get inside the cells and go through them there have to be transporters which specifically allow glucose to pass into the cell and then out into our body.

为使其能进入并穿过细胞,肠上皮必须具有葡萄糖特异性的转运蛋白,使葡萄糖能够穿过细胞进入体内

耶鲁公开课 - 生物医学工程探索课程节选

Those are called glucose transporters.

这些分子叫做葡萄糖转运载体

耶鲁公开课 - 生物医学工程探索课程节选

Insulin, the ligand binds to its receptor, creates a change through a kinase activity that's exposed, which leads to other biochemical changes, which leads to a change in cell behavior - in this case the cell behavior is that more glucose transporters are brought to the membrane and more glucose can enter the cell.

胰岛素,一种能够与受体结合的配体,通过其暴露出的激酶活性引起的变化,导致了其它后续生化变化的发生,进而使细胞行为发生改变,这个例子中的细胞行为就是,更多的糖载体被带到细胞膜表面,这样更多的糖分子进入到细胞内部

耶鲁公开课 - 生物医学工程探索课程节选