Well the way to find it is by using a process called electrophoresis and Southern blotting.

找到二者差异的方法称作电泳和,琼脂糖凝胶电泳印迹

耶鲁公开课 - 生物医学工程探索课程节选

If this was a sickle patient, so they had this gene instead it wouldn't get cut and when I went to look for that presence of that gene on this gel, it would appear as one large segment instead of a large one and a smaller one.

而如果是个镰状红细胞贫血的病人,他们的基因是不会被限制酶切割的,因此他们基因的凝胶电泳结果就不会呈现,一大一小的结果,而只有一个大的片段

耶鲁公开课 - 生物医学工程探索课程节选

I'm sure some of you have dealt with electrophoresis gels in the past and it's really just a slab of something like Jell-O where you can put a sample at one end of the Jell-O, your sample of fragmented DNA.

我相信在座肯定有些已经接触过电泳凝胶,真的挺像一块板状果冻的,你可以把一段样本放在"果冻"的一端,你的DNA片段样本

耶鲁公开课 - 生物医学工程探索课程节选

We're going to take a chromosomal DNA, we're going to digest it with this restriction enzyme, we're going to put it in this tube and run it on a gel, and we're going to see what results down here.

我们取一条染色体DNA,然后用限制酶进行分解,接着再放,在凝胶上进行电泳,之后看看结果如何

耶鲁公开课 - 生物医学工程探索课程节选