It turns out when you give Aldopa to people, it gets converted biochemically into natural dopamine which then serves as its own agonist.
已经证明如果向人体中引入阿多巴,它就能通过生化过程转化为多巴胺,发挥激动剂作用
An agonist is a substance that mimics the action of a natural ligand, and I show you a couple of examples of agonists here.
激动剂是能够模拟天然配体分子的物质,在这里我给出了一些激动剂作为例子
And what an agonist does is increases the effect of neurotransmitters, either by making more neurotransmitters or stopping the cleanup of neurotransmitters, or in some cases by faking a neurotransmitter, by mimicking its effects.
兴奋剂会增加神经递质的作用效果,有可能是通过释放更多的神经递质而实现,也可能是通过阻止神经递质的排出而实现,也有时候是通过伪造神经递质,通过模仿神经递质的效果来实现的
Now, sometimes the agonist is the natural ligand itself and that's - an example of that is when you use insulin as a drug.
有时激动剂药物就是天然配体分子,例如将胰岛素作为药物使用
We've identified many drugs that stimulate insulin receptors, for example, but they're not exactly insulin, and those can potentially be used as agonist type drugs.
我们已经设计了很多,能够激活胰岛素受体的药物,但它们都不是和胰岛素分毫不差的,但都可以用作激动剂类药物
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