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That can happen but that's abnormal, but changes in maybe the chemistry of the backbone that holds the nucleotides together.
这可能发生的,但属于非正常的变化,而是改变诸如维持核苷酸序列的,主链的化学结构
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This material will be necessary to do the listening exercises for the course, which is sort of the backbone of the course.
做听力练习时我们必须使用这些材料,听力训练是课程的核心内容
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One thing to notice is this part of the double helix that we'll call the backbone.
要注意的是,这两股构成双螺旋的链我们称之为主链
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He is independent in a way that nobody who was not a king or an aristocrat in the past has ever been -- a new kind of man, the backbone of the polis as it emerges.
他是如此的独立以至于,前无古人后无来者,一个全新的人,它不断地发展并成为城邦制的脊梁
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So what's going to form the backbone is this continual link, phosphate to sugar, phosphate to sugar, phosphate to sugar, all linked together to form one long, long molecule.
主链是由这样重复的连接构成的,从磷酸到戊糖,周而复始,所有这些连接起来构成一个长链分子
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The backbone is what?
主链是什么
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This represents the upright struts on a ladder that I showed you before, it represents this backbone that's shown by - that's formed by polymerizing the pentose's together through phosphate's always going 5' to 3', 5' to 3'.
线条代表梯子,上下的支柱 之前给你们演示过,代表由多聚戊糖分子,通过磷酸基从5'端向3'端方向,连接起来的主链
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It's the phosphate and the pentose that make up the backbone - that make up the upright struts of the ladder and it's the bases that make up the connecting struts, so the bases are the colors.
磷酸基和戊糖,共同构成了主链,主链又构成了梯子上下的支柱,而碱基,则构成连接支柱的梯阶,碱基是用各种颜色表示的
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The backbone's on the outside of the molecule like the upright struts of a ladder on the outside of a ladder.
主链位于DNA分子结构外侧,像梯子两侧上下的支柱,记住是梯子外侧
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In some cases that backbone gets methylated and those regions of the DNA that are methylated get treated differently by the cell than unmethylated regions.
一些情况下,主链会甲基化,该甲基化区域的DNA,和未甲基化区域的DNA,会被细胞区别对待
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Every unit in the backbone of this ladder has the same sugar unit, the same pentose; it's either RNA or DNA and has ribose or deoxyribose, so you don't need to describe the whole thing.
主链的每个单位,都由相同的糖单位构成,同样的戊糖,RNA里是核糖,DNA里是脱氧核糖,所以你不需要所有细节都描述
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