• That matrix has properties that vary in different locations in the body, but basically it's a highly hydrated or water-rich gel.

    这种基质的性质,随其所在身体部位的不同而不同,但基本是高度水合的,即富含水的凝胶

    耶鲁公开课 - 生物医学工程探索课程节选

  • This collagen is highly hydrated, it forms a gel that has water-like properties but it also has solid properties.

    这些胶原蛋白是高度水合的,形成了既有水的特性,又具有固体特性的胶体

    耶鲁公开课 - 生物医学工程探索课程节选

  • The extracellular matrix or the collagen gel gives the tissue integrity, and in part, determines its mechanical properties.

    细胞外基质或者说胶原蛋白凝胶,使组织成为一个整体,在某种程度上,决定了组织的机械性能

    耶鲁公开课 - 生物医学工程探索课程节选

  • If I can run the gel for some period of time, run the electrical field, spread it out.

    我将凝胶通电一段时间后,在电场作用下,就会分散开来

    耶鲁公开课 - 生物医学工程探索课程节选

  • We talked last time about extracellular matrix and this complex protein-carbohydrate gel that surrounds all cells.

    我们上次谈到过的细胞外基质,是一种蛋白和碳水化合物的复合物胶冻,它环绕在细胞周围

    耶鲁公开课 - 生物医学工程探索课程节选

  • You load them into the top of a gel and a gel is - in this case it's synthetic polymer gel but it looks very much like Jell-O.

    你把它安置在一段凝胶上,凝胶是--,这种合成凝胶聚合物看上去很像吉露果冻

    耶鲁公开课 - 生物医学工程探索课程节选

  • Because it's a gel electricity is going to move through the gel because there are ions in it the same way - for the same reason you don't drop an electrical device into the bathtub because charge moves through water that has ions in it.

    由于凝胶中存在离子,电流会通过凝胶,同样--,因为同样的原因你不会把电器扔进浴缸里,因为水里也有离子,所以水可以导电

    耶鲁公开课 - 生物医学工程探索课程节选

  • If this was a sickle patient, so they had this gene instead it wouldn't get cut and when I went to look for that presence of that gene on this gel, it would appear as one large segment instead of a large one and a smaller one.

    而如果是个镰状红细胞贫血的病人,他们的基因是不会被限制酶切割的,因此他们基因的凝胶电泳结果就不会呈现,一大一小的结果,而只有一个大的片段

    耶鲁公开课 - 生物医学工程探索课程节选

  • Charge is going to move through this gel and DNA is charged.

    电流会通过凝胶而DNA是带有电荷的

    耶鲁公开课 - 生物医学工程探索课程节选

  • Now if I can stain in some way, if I can somehow label the DNA fragments that I'm interested in, I could find out where those fragments are on this gel.

    那如果我有某种染色的方法,对我感兴趣的DNA片段进行标记,我就能知道这些片段在凝胶板上的位置

    耶鲁公开课 - 生物医学工程探索课程节选

  • We're going to take a chromosomal DNA, we're going to digest it with this restriction enzyme, we're going to put it in this tube and run it on a gel, and we're going to see what results down here.

    我们取一条染色体DNA,然后用限制酶进行分解,接着再放,在凝胶上进行电泳,之后看看结果如何

    耶鲁公开课 - 生物医学工程探索课程节选

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