• They might ingest extracellular antigen, presented pieces of it on their cell surface in the context of MHC-2.

    它们可以吞噬胞外抗原,根据细胞表面的,主要组织相容性抗原-2

    耶鲁公开课 - 生物医学工程探索课程节选

  • It can separate between what's part of yourself and what's foreign, and it does that by presenting, by recognizing antigens that are presented in the context of the major histocompatibility complex, MHC.

    免疫系统可以识别出哪些是属于你的,哪些是外来的,它通过呈递和识别抗原达到目的,而抗原是存在于,主要组织相容性复合体中的

    耶鲁公开课 - 生物医学工程探索课程节选

  • One of the functions of MHC is to indicate which cells belong inside your body, which cells don't.

    HC的功能之一,是区分哪些细胞属于你的身体,而哪些不属于

    耶鲁公开课 - 生物医学工程探索课程节选

  • These cells can now kill cells that have the correct signature, and the signature is MHC-1 with this foreign antigen associated with it.

    而这些细胞现在可以杀伤带标记的细胞,这些标记就是MHC-1表面受体,和与其相联的异己抗原

    耶鲁公开课 - 生物医学工程探索课程节选

  • Each one of our cells - one of the things that distinguishes them is the kind of MHC molecules that all of my cells make.

    我们的每一个细胞--,能够使它们相区分的,就是它们所产生的MHC分子

    耶鲁公开课 - 生物医学工程探索课程节选

  • Because it has MHC-1, your MHC-1 on it, this T-cell recognizes that it's one of your cells but it has a foreign antigen associated with it.

    因为该细胞上有MHC-1,T细胞将这些细胞识别为自身细胞,但这些细胞带有异己抗原

    耶鲁公开课 - 生物医学工程探索课程节选

  • I talked last time about MHC - on the last slide about MHC1.

    我上次谈过MHC,在MHC1的最后一张幻灯上

    耶鲁公开课 - 生物医学工程探索课程节选

  • An antigen expressed in the context of MHC stimulates your immune system.

    MHC共同表达的抗原,激活了免疫系统

    耶鲁公开课 - 生物医学工程探索课程节选

  • MHC1 is a word, MHC stands for major histocompatibility complex and it's one of the things that distinguishes my cells from your cells, from your parents cells, from your roommates cells.

    HC1这个词,MHC代表主要组织相容性复合体,通过它可以区分你和我的细胞,也可以区分你和你父母,及你室友的细胞

    耶鲁公开课 - 生物医学工程探索课程节选

  • We talked about host cells that are perhaps infected with a virus, displaying pieces of that virus, antigenic pieces of that virus in the context of a surface receptor called MHC-1, presenting that.

    我们说到过,可能受到病毒感染的宿主细胞,表现出病毒的一部分特征,病毒的抗原部分,其表面受体称为主要组织相容性抗原-1,MHC-1负责呈递抗原

    耶鲁公开课 - 生物医学工程探索课程节选

  • Then those antigens get expressed with MHC just like they did in all the other cells inside the host, but particular cells of the innate immune system have a different kind of MHC called MHC2.

    这些抗原同MHC共表达,就如同抗原在其他宿主细胞中那样,但先天免疫系统有一类特殊的免疫细胞,具有一种称为MHC2的不同MHC

    耶鲁公开课 - 生物医学工程探索课程节选

  • If you take an organ from one person and put it in another, if their MHC molecules don't match then the immune system recognizes the immune system of the host recognizes 'this is not the right MHC for me' and the immune tries to destroy those cells.

    如果将器官从一个人移植到另一个人,免疫系统识别出MHC分子并不匹配,宿主的免疫系统就会说,这不是我的MHC,免疫系统就会试着摧毁移植器官的细胞

    耶鲁公开课 - 生物医学工程探索课程节选

  • One of the other things that MHC1 does, in addition to marking yourselves as your own, is that it's capable of making combinations with all the different molecules that are present inside the cell and expressing them on the surface, and sort of showing them to the outside world.

    HC1的另一项功能,除了给你标记一个独一无二的标签以外,MHC可以和细胞内所有不同的,分子结合 使其能够呈现在细胞表面,使其暴露于外界

    耶鲁公开课 - 生物医学工程探索课程节选

$firstVoiceSent
- 来自原声例句
小调查
请问您想要如何调整此模块?

感谢您的反馈,我们会尽快进行适当修改!
进来说说原因吧 确定
小调查
请问您想要如何调整此模块?

感谢您的反馈,我们会尽快进行适当修改!
进来说说原因吧 确定