• It's easy to know what nucleotide to put in each position as you're going along and polymerizing a new molecule.

    这使得复制过程中决定下一个核苷酸位点,应该用哪一个核苷酸更为容易

    耶鲁公开课 - 生物医学工程探索课程节选

  • That's due to the asymmetry of the nucleotide, that there's a 5' and a 3' end and the way that they're linked together.

    这是由于核苷酸的非对称性造成的,这里是5'端和3'端,这就是它们连接在一起的方式

    耶鲁公开课 - 生物医学工程探索课程节选

  • The phosphate group of one nucleotide gets linked to the sugar group of another nucleotide and I'm going to show you that in a few minutes.

    一个核苷酸上的磷酸基团,连接在另外一个核苷酸的糖基上,马上我会给你们演示

    耶鲁公开课 - 生物医学工程探索课程节选

  • I would attach the phosphate that's connected to the 5' carbon of another nucleotide.

    我会添加一个磷酸基团到,另外一个核苷酸的5'碳原子上

    耶鲁公开课 - 生物医学工程探索课程节选

  • In nucleotide the phosphate is always attached to the 5' carbon.

    在核苷酸内磷酸基总是连接到5'碳部位

    耶鲁公开课 - 生物医学工程探索课程节选

  • The nucleotide has a directionality, there's an up and a down to it and it's going to turn out the chain that's formed by polymerizing these has a directionality as well and that's important in defining the structure.

    核苷酸有方向性,有上端和下端,核苷酸长链,是由核苷酸沿一个特定方向聚合而成的,这在定义结构时很重要

    耶鲁公开课 - 生物医学工程探索课程节选

  • The reason that 3' is important is that when you polymerize two nucleotides together and a third nucleotide, and a fourth nucleotide, when you polymerize nucleotides together they get polymerized, the phosphate of one gets linked to the 3' carbon of another.

    '碳部位重要是因为,当你把两个核苷酸聚合在一起,然后再聚合第三个,第四个的时候,核苷酸在聚合时,磷酸基与另外一个戊糖的3'碳部位连接

    耶鲁公开课 - 生物医学工程探索课程节选

  • If I wanted to link another nucleotide to this DNA chain what would I attach here on the bottom?

    如果想把另一核苷酸连接到这条DNA链,我将会在DNA链末端添加什么

    耶鲁公开课 - 生物医学工程探索课程节选

  • So the repeating unit in DNA is this structure here, a nucleotide, which has three different regions.

    NA的重复单位就是,核苷酸,它有三个不同的区域

    耶鲁公开课 - 生物医学工程探索课程节选

  • If I told you that 'draw me a nucleotide from RNA that has ', you could go back to this picture and you could draw the whole thing.

    如果让你找RNA中碱基是A的核苷酸,你可以看着这个图,就能找出其全部结构

    耶鲁公开课 - 生物医学工程探索课程节选

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