There are two classes, two broad classes of drug sort of type ligands that are defined, agonists and antagonists.

这样的配体药物有两类,目前已经明确的配体药物大体上分为两种,分别是激动剂和拮抗剂

耶鲁公开课 - 生物医学工程探索课程节选

It turns out when you give Aldopa to people, it gets converted biochemically into natural dopamine which then serves as its own agonist.

已经证明如果向人体中引入阿多巴,它就能通过生化过程转化为多巴胺,发挥激动剂作用

耶鲁公开课 - 生物医学工程探索课程节选

An agonist is a substance that mimics the action of a natural ligand, and I show you a couple of examples of agonists here.

激动剂是能够模拟天然配体分子的物质,在这里我给出了一些激动剂作为例子

耶鲁公开课 - 生物医学工程探索课程节选

Now, sometimes the agonist is the natural ligand itself and that's - an example of that is when you use insulin as a drug.

有时激动剂药物就是天然配体分子,例如将胰岛素作为药物使用

耶鲁公开课 - 生物医学工程探索课程节选

We've identified many drugs that stimulate insulin receptors, for example, but they're not exactly insulin, and those can potentially be used as agonist type drugs.

我们已经设计了很多,能够激活胰岛素受体的药物,但它们都不是和胰岛素分毫不差的,但都可以用作激动剂类药物

耶鲁公开课 - 生物医学工程探索课程节选