-
That can happen but that's abnormal, but changes in maybe the chemistry of the backbone that holds the nucleotides together.
这可能发生的,但属于非正常的变化,而是改变诸如维持核苷酸序列的,主链的化学结构
-
It's easy to know what nucleotide to put in each position as you're going along and polymerizing a new molecule.
这使得复制过程中决定下一个核苷酸位点,应该用哪一个核苷酸更为容易
-
What's hanging off of the side of this long molecule that's formed by polymerizing nucleotides are - is this base unit.
在这条由多聚核苷酸,构成的长链分子,一侧悬挂着碱基单位
-
So you made somehow an anti-sense polynucleotide to the insulin gene or some fraction of the insulin gene.
这样你就合成了,胰岛素基因的反义多聚核苷酸链,或者说胰岛素基因的片段
-
That's due to the asymmetry of the nucleotide, that there's a 5' and a 3' end and the way that they're linked together.
这是由于核苷酸的非对称性造成的,这里是5'端和3'端,这就是它们连接在一起的方式
-
The phosphate group of one nucleotide gets linked to the sugar group of another nucleotide and I'm going to show you that in a few minutes.
一个核苷酸上的磷酸基团,连接在另外一个核苷酸的糖基上,马上我会给你们演示
-
You know that these molecules are also linked in another way, by the phosphate bonds that connect the 3 and the 5 carbons of adjacent nucleotides.
这些分子还通过别的方式连接在一起,例如通过相邻核苷酸的3碳位和,5碳位之间的磷酸键相连
-
I would attach the phosphate that's connected to the 5' carbon of another nucleotide.
我会添加一个磷酸基团到,另外一个核苷酸的5'碳原子上
-
In nucleotide the phosphate is always attached to the 5' carbon.
在核苷酸内磷酸基总是连接到5'碳部位
-
The digestive system, of course, is responsible for bringing in sort of fresh nutrients, fresh substrates for cellular metabolism, fresh quantities of amino acids, and nucleotides, and the things that we can't generate internally.
当然,还有消化系统,它主要负责将各种新鲜营养物摄入体内,为细胞代谢提供新的底物,如一批新的氨基酸,核苷酸,以及那些人体无法自行合成的东西
-
The nucleotide has a directionality, there's an up and a down to it and it's going to turn out the chain that's formed by polymerizing these has a directionality as well and that's important in defining the structure.
核苷酸有方向性,有上端和下端,核苷酸长链,是由核苷酸沿一个特定方向聚合而成的,这在定义结构时很重要
-
The reason that 3' is important is that when you polymerize two nucleotides together and a third nucleotide, and a fourth nucleotide, when you polymerize nucleotides together they get polymerized, the phosphate of one gets linked to the 3' carbon of another.
'碳部位重要是因为,当你把两个核苷酸聚合在一起,然后再聚合第三个,第四个的时候,核苷酸在聚合时,磷酸基与另外一个戊糖的3'碳部位连接
-
You can just say it's RNA or DNA and you know everything about the pentose in every molecule on the chain.
你只需要说它是一个RNA或者DNA,就能知道,每个核苷酸分子的戊糖
-
If I wanted to link another nucleotide to this DNA chain what would I attach here on the bottom?
如果想把另一核苷酸连接到这条DNA链,我将会在DNA链末端添加什么
-
You take advantage of that, you put it in a test tube, together with nucleotides and primers and your DNA.
利用这一点,把它和核苷酸,引物及DNA一起放进试管
-
So the repeating unit in DNA is this structure here, a nucleotide, which has three different regions.
NA的重复单位就是,核苷酸,它有三个不同的区域
-
When these nucleotides get polymerized to form a long DNA molecule they all get polymerized in exactly the same way, the chemistry is the same.
当这些核苷酸多聚化,形成一条长链DNA分子时,它们的聚合方式和,化学结构都完全相同
-
Now, in your book, there's an example of plasmid where I've given you the exact sequence of nucleotides that makes up the whole double stranded DNA molecule.
现在在你们书里,有个质粒样本,我将组成这个双链DNA分子的,核苷酸序列写在这里了
-
You do that together with primers and with nucleotides, because if you're going to synthesize DNA you need the raw material of DNA, you need the individual nucleotides.
同时把引物和核苷酸放进去,因为合成DNA需要原料,你需要单个的核苷酸
-
If I told you that 'draw me a nucleotide from RNA that has ', you could go back to this picture and you could draw the whole thing.
如果让你找RNA中碱基是A的核苷酸,你可以看着这个图,就能找出其全部结构
-
Nucleic acids, of which DNA is an example, are polymers of nucleotides.
核酸以及其中的DNA分子就是个例证,核酸就是核苷酸聚合物
-
You can say a polymer of DNA, for example, is four bases long, that means it has four of these repeat units and they go in the sequence from 5' to 3' of .
打个比方,要描述一个由,四个核苷酸单位构成的寡聚DNA,就是说它由四个核苷酸单位构成,并且从5'端到3'端的顺序为
-
Some of them are changes in the - not the sequence of DNA, not the sequence of nucleotides in the DNA but the chemistry of DNA around that the way that it's packed into a nucleus.
某些改变不是发生在DNA序列上,不是在DNA的核苷酸序列上,而是发生在DNA包装进细胞核的,一系列化学变化中
应用推荐