His face was swollen (up) with tooth ache.
他的脸因牙痛而肿了起来。
First is physical pain like tooth ache, body ache, back pain, neck pain etc. and second is heart pain.
第一种是生理上的，像牙痛，身上痛，背痛，脖子痛等等，第二种是心痛。
I have a terrible headache, I have a terrible stomach-ache, I have a terrible tooth-ache.
我头疼的厉害，我胃疼的厉害，我牙疼的厉害。
我的牙很痛。
The medicine has soothed the ache in my tooth.
这药缓解了我的牙疼。
The ache in the tooth is off and on.
这个牙一会儿疼，一会儿又不疼。
The ache in the tooth is off and on.
这个牙一会儿疼，一会儿又不疼。
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