CONCLUSION: The insulin-liposomes double-coated with chitosan and CEC were in favor of improving oral bioavailability of insulin.
结论:壳聚糖- CEC双层包覆胰岛素脂质体有利于改善胰岛素口服生物利用度。
The oral bioavailability of the active compounds in the pharmaceutical compositions of the present invention is surprisingly high.
本发明药物组合物中活性化合物的口服生物利用度之高是惊人的。
PTK787 is the most promising VEGF receptor- tyrosine kinase inhibitor in pipeline because of its potency in tumor inhibition and oral bioavailability.
PTK787因其对肿瘤抑制的出色疗效、口服生物利用度高等特点而成为VEGF受体酪氨酸激酶抑制剂中的佼佼者。
Many studies show that 4-oxo-dihydroquinolines have good oral bioavailability and plasma clearance, and they suppress both the DNA polymerase of HSV and virus replication in the cells.
多项研究表明,4 -氧代二氢喹啉类有良好的口服利用率及中等程度的血浆清除率,不仅对核苷酸聚合酶产生抑制,还可以抑制细胞内的病毒复制。
Factors that affect the oral bioavailability of water insoluble drugs were discussed, and a review was given on the measures of improving the oral bioavailability of water insoluble drugs.
讨论了影响自胃肠道吸收药物生物利用度的因素,对提高难溶性药物口服生物利用度的方法进行了综述。
Oral albendazole liposomes has shown higher bioavailability and liver targeting in comparison with tablet formulation.
口服阿苯达唑脂质体有较高的生物利用度并有一定的肝脏靶向性。
The SEDDS can dramatically improve the bioavailability of poorly water soluble or lipophilic drugs by oral administration. SEDDS will have a good developmental potential.
自乳化药物传递系统可显著地提高难溶性或亲脂性药物口服生物利用度,具有广阔的发展前景。
This drug has low bioavailability, adverse reaction of gastrointestinal tract by oral administration, and is administered frequency.
炔雌醇口服生物利用度低,有胃肠道副作用,日给药次数多。
In this work, SOD gelatin microspheres were made with the aim to improve its stability, oral relative bioavailability, and to study the preparation conditions of microspheres.
本工作将SOD制成微球,以提高SOD稳定性和口服相对生物利用度,且在微球制备条件方面作了进一步研究。
Most oral dosage forms of FP had low bioavailability because FP could hardly dissolve.
FP的口服制剂中,大多存在溶出难和生物利用度低的问题。
Many of the oral antibiotics prescribed in the Ed have good bioavailability.
在急诊科开具的很多口服抗生素均具有很好的生物利用度。
But the oral dosage forms of Breviscapine are poorly absorbed in body, and they have low absolute bioavailability.
但灯盏花素口服剂型吸收较差,绝对生物利用度低,而注射给药给长期治疗的病人带来许多不便和痛苦。
There are many challenges in developing an oral formulation of GLP-1, in particular obtaining adequate bioavailability.
开发口服型的GLP-1药物存在许多难题,尤其是需要有足够的生物利用度。
However, for the sake of its low oral absorption and bioavailability, now in clinic Puerarin is administrated only by vein injection, which is inconvenient for patients and limits its clinical use.
由于其口服难吸收、生物利用度低的原因,临床只用于静脉给药。这不仅给患者带来用药的不便,而且也限制了葛根素的临床应用。
Objective To manufacture a high bioavailability oral insulin that fit the blood glucose change after meals.
目的研制一种生物利用度高适合餐后血糖变化模式的胰岛素口服制剂。
Background: As one of the histamine H_2 receptor antagonist, the oral absorption of famotidine is not complete, its bioavailability is about 37%-50%.
背景:法莫替丁作为组胺H_2受体拮抗剂,其口服吸收不完全,生物利用度约为37% - 50%。
AIM: To compare pharmacokinetics and bioavailability of 2 midazolam tablets in 20 healthy volunteers after a single oral dose (15 mg) of domestic midazolam maleate tablets compared with imported.
目的:比较国产和进口马来酸咪达唑仑片在2 0名男性健康受试者中的药物动力学和相对生物利用度。
Low bioavailability is most common with oral dosage forms of poorly water-soluble, slowly absorbed drugs.
低生物利用度最常见于水溶性差、吸收慢的药物的口服剂型。
The relative bioavailability of baicalein nanosuspension by oral administration were 166.1%.
以黄芩素给药做参比,黄芩素纳米混悬液给药的相对生物利用度为166.1%。
Baicalein nanosuspension by oral administration could significantly enhance the bioavailability in rats.
黄芩素纳米混悬液口服给药可显著提高生物利用度。
Baicalein nanosuspension by oral administration could significantly enhance the bioavailability in rats.
黄芩素纳米混悬液口服给药可显著提高生物利用度。
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