目的：合成基质金属蛋白酶抑制剂伊洛马司他。
Objective: To synthesize ilomastat, a matrix metalloproteinase inhibitor.
目的：评价基质金属蛋白酶抑制剂临床应用的疗效与安全性。
OBJECTIVE: to evaluate the efficiency and safety of matrix metallo-proteinase inhibitor in clinical application.
本发明提供了一类强效的基质金属蛋白酶抑制剂，可有效治疗基质金属蛋白酶活性异常表达的疾病。
One kind of powerful matrix metalloprotease inhibitor is provided to treat disease with abnormal matrix metalloprotease activity expression effectively.
目的研究基质金属蛋白酶-2（MMP-2）及其抑制物组织基质金属蛋白酶抑制剂-2（TIMP-2）在大肠癌进展中的作用及其临床意义。
Purpose To understand the relationship between the expression of MMP-2, TIMP-2 and the clinical significance in human colorectal carcinoma.
目的：研究基质金属蛋白酶-2 (MMP - 2)和组织基质金属蛋白酶抑制剂- 2 (TIMP - 2)在人肺癌组织中的表达及其与微血管密度(MVD)的关系。
Objective to study the expressions of metalloproteinase 2 (MMP-2) and tissue inhibitors of metalloproteinase 2 (TIMP-2) in lung cancer, and their relationships with microvessel density (MVD).
目的研究基质金属蛋白酶2 (MMP 2)和金属蛋白酶组织抑制剂2 (TIMP 2)在人脑星形细胞瘤中的表达及其与病理分级的关系。
Objective to investigate the expressions of matrix metalloproteinase 2 (MMP 2) and tissue inhibitor of metalloproteinase 2 (TIMP 2) in astrocytoma and their relations to the pathological grade.
结论PUVA治疗引起的皮肤光老化皱纹形成可能与真皮成纤维细胞基质金属蛋白酶及其组织抑制剂表达失衡密切相关。
Conclusion Wrinkle formation in photoaging skin after PUVA therapy is correlated with the imbalance of expression of matrix metalloproteinases and their inhibitors of dermal fibroblasts.
目的探讨基质金属蛋白酶-2 (MMP - 2)和组织基质金属蛋白抑制剂- 2 (TIMP - 2)在胃癌组织中的表达及其与侵袭程度、淋巴结转移的关系。
Objective to study the expression of MMP 2 and TIMP 2 in gastric cancer tissues and the relation to the aggregated degree, metastasis and prognosis.
目的探讨基质金属蛋白酶- 2 (MMP - 2)，组织金属蛋白酶抑制剂- 2 (TIMP - 2)在食管鳞癌中的表达及其临床意义。
Objective to investigate the expressions of matrix metalloproteinase-2 (MMP-2) and the tissue inhibitor of metalloproteinases-2 (TIMP-2) in human esophageal squamous cell carcinoma (ESCC).
目的探讨基质金属蛋白酶-2（MMP-2）和组织基质金属蛋白抑制剂-2（TIMP-2）在大肠癌组织中的表达及其意义。
Objective To study the expression and significance of MMP-2 and TIMP-2 in colorectal carcinoma.
目的研究基质金属蛋白酶MMP-2及其抑制剂TIMP-2在颅咽管瘤中的表达意义。
Objective To study the significance of matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of metalloproteinase-2 (TIMP-2) expressing in craniopharyngiomas.
目的：研究基质金属蛋白酶-1（MMP-1）、金属蛋白酶组织抑制剂-1（TIMP-1）、增殖细胞核抗原（PCNA）在病理性瘢痕中的表达及意义。
Objective To study the significance of expression of Matrix Metalloproteinase-1(MMP-1) , Tissue Inhibitor of Metalloproteinase-1(TIMP-1) and Proliferating cell nuclear antigen (PCNA) in abnormal scar.
目的研究过量氟对大鼠切牙生长过程中基质金属蛋白酶-20（MMP-20）和基质金属蛋白酶组织抑制剂-2（TIMP-2）表达的影响，探讨氟斑牙的发病机制。
Objective To investigate the effects of overdosed fluoride on the expression of MMP-20 and TIMP-2 in rat incisor.
脑缺血；黄体酮；基质金属蛋白酶9；金属蛋白酶组织抑制剂1；血脑屏障。
Cerebral ischemia; Blood brain barrier; Progesterone; Matrix metalloproteinase9; Tissue inhibitor of metalloproteinase1.
脑缺血；黄体酮；基质金属蛋白酶9；金属蛋白酶组织抑制剂1；血脑屏障。
Cerebral ischemia; Blood brain barrier; Progesterone; Matrix metalloproteinase9; Tissue inhibitor of metalloproteinase1.
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