目的：评价尼美舒利对慢性牙周炎的治疗效果。
AIM: To evaluate the effect of nimesulide on chronic periodontitis.
目的：用高效液相色谱法测定尼美舒利的含量。
OBJECTIVE: To determine the content of nimesulide (nim) by HPLC method.
本发明涉及一种尼美舒利化合物及其纯化方法。
The invention relates to a Nimesulide compound and a purification method thereof.
目的：考察不同浓度的透明质酸对尼美舒利凝胶的透皮促进作用。
Objectives: To study the transdermal effect of different concentration of hyaluronan in promoting nimesulide gel in vitro.
近年，尼美舒利引致肝脏损害，甚至死亡，而在一些国家停止销售。
Recently, in some countries nimesulide has been withdrawn from the market because of nimesulide-induced severe liver injury and death.
方法考察粘合剂浓度、研磨时间、压片力对尼美舒利片溶出度的影响。
Methods: the effect of adhesive concentration, milling time and pressure on the dissolution of Nimesulide tablets were studied.
目的探讨尼美舒利对体外培养的结肠癌细胞生长及细胞周期分布的影响。
Objective To evaluate the potential role of nimesulide on the proliferation and cell cycle distribution of colon adenocarcinoma cell lines.
结果：尼美舒利能增强二硝基氟苯诱导的迟发型变态反应，并且提高抗体水平增加脾脏重量。
Result: The severity of dinitrofluorobenzene-induced delay type of hypersensitivity was enhanced by nimesulide, the antibody level and weight of spleen were increased.
“尼美舒利”最早于1985年在意大利上市，目前它在全世界50多个国家和地区使用，该药品于1997年进入中国市场。
Nimesulide first became available in Italy in 1985. It is now used in more than 50 countries and regions all over the world. The drug entered the Chinese market in 1997.
“尼美舒利”最早于1985年在意大利上市，目前它在全世界50多个国家和地区使用，该药品于1997年进入中国市场。
Nimesulide first became available in Italy in 1985. It is now used in more than 50 countries and regions all over the world. The drug entered the Chinese market in 1997.
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