估计3600万到5700万美国人是胰岛素抵抗。
An estimated 36 million to 57 million Americans are insulin-resistant.
其中之一是胰岛素抵抗是非酒精性脂肪肝人群中很普遍的一个现象。
One of them is insulin resistance is a universal phenomenon in persons who have nonalcoholic fatty liver disease.
在2型糖尿病胰岛素的产生，是在低水平，有时候甚至有可能是胰岛素抵抗。
In Diabetes Type 2 the production of insulin is low and sometimes there may be resistance to insulin.
炎症在胰岛素抵抗发生机制中占有重要地位，可能是胰岛素抵抗的致病介质。
Inflammation appears to play an important role in the mechanism of insulin resistance and may be the mediator to develop to metabolic disorder syndrome.
肥胖者空腹血清瘦素水平与胰岛素抵抗密切相关，是胰岛素抵抗的主要相关因素，而这一关系仅在男性中存在。
Fasting serum leptin level closely correlated with insulin resistance in obese subjects and it was the main correlation factor of insulin resistance, but the relationship only existed in male.
其与炎症因子的相互作用可能是脂联素增强胰岛素敏感性的机制之一，也可能是胰岛素抵抗时低脂联素血症的原因。
The interaction of adiponectin and inflammatory cytokines maybe one of the mechanisms which increases insulin sensitivity, and maybe the source of hypoadiponectin in insulin resistance.
结论高血压患者RAS活性增加与血浆胰岛素浓度增加密切相关，RAS活性增加可能是胰岛素抵抗(IR)的原因之一。
Conclusion the increased activity of RAS is correlated with the hyperinsulinemia and may be one of the causes of insulin resistance (IR).
信息来自于IRAS家庭研究中的1107名受试者，这项家庭研究是胰岛素抵抗的动脉粥样硬化研究(IRAS)的延伸。
Information was obtained from 1,107 people in the IRAS Family Study, an extension of the Insulin Resistance Atherosclerosis Study (IRAS).
导致糖尿病的对胰岛素的抵抗看来是由聚积在肌肉细胞和肝脏内的脂肪引起的。
The resistance to insulin that leads to diabetes appears to be caused by a build-up of fat inside the muscle cells and also inside the liver.
单凭这些，这些实验结果并不证明胰岛素抵抗是对肥胖者吃得多倾向的解释。
By themselves, these results do not prove that insulin-resistance is the explanation for the tendency of the already-lardy to eat too much.
其他的一些研究已经表明，大量摄取果糖会影响人体对葡萄糖的代谢，并会加重人体对胰岛素的抵抗力，而这两者是判断是否可能罹患糖尿病的重要指标。
Other studies have shown that high fructose intake can affect how the body handles glucose and increases insulin resistance — which can both be important measures of the tendency toward diabetes.
肥胖与胰岛素抵抗有关，是2型糖尿病、心脏病、高血压和其他慢性病的危险因素。
Associated with insulin resistance, obesity is a risk factor for type 2 diabetes, heart disease, hypertension and other chronic illnesses.
在他们的综述中，科学家们指出过去几十年报告的发现与关于EPA和DHA对人类志愿者胰岛素抵抗的影响是相矛盾的。
In their review, the scientists indicate that findings reported in the past decade have been inconsistent in regard to the effects of EPA and DHA on insulin resistance in human volunteers.
细胞及动物水平的研究结果提示，胰岛素抵抗可能是其中的重要因素。
Findings at a cellular level and in animals suggest insulin resistance may be an important factor in this.
但是一些专家相信是人体抵抗疾病的防御机制由于一些原因破坏了产生胰岛素的细胞。
But some experts believe the body's defenses against disease for some reason destroy the cells that produce insulin.
胰岛素抵抗是与体重指数相关的重要指标，被认为能更准确地反应脂肪的代谢效应。
Insulin resistance is also an important correlate of BMI and is perceived as a more accurate marker of the metabolic effect of obesity.
因而单独胰岛素抵抗不可能是T2DM的决定性致病因素。
Therefore, insulin resistance alone can not be the determining pathogenic factor in T2DM.
代谢综合症是对一系列脂蛋白异常情况的总称，如：高血压、肥胖症、胰岛素抵抗，以及会导致心脏病和糖尿病风险的胆固醇过高。
Metabolic syndrome, a collection of related abnormalities like hypertension, obesity, insulin resistance, and excess cholesterol, poses a major risk for developing heart disease and diabetes.
运动能改善胰岛素抵抗，但究其干预的确切机制是发生在胰岛素受体水平还是受体后水平目前尚无定论。
Exercise can improve insulin resistance, but the specific mechanism of insulin resistance exercise induced on the level of receptor or post-receptor is not sure.
《国际糖尿病》：二甲双胍通常被看作是胰岛素增敏剂。在改善胰岛素抵抗方面，二甲双胍和吡格列酮的区别有哪些？
International Diabetes: metformin is often viewed as an insulin sensitizer. What is the difference between metformin and pioglitazone with regard to improving insulin resistance?
患有2型糖尿病儿童的家长们得知，他们超重的孩子身上那顽固的脏皮肤原来是黑棘皮病，一种胰岛素抵抗的症状。
Parents of children with type 2 diabetes learn that what they thought was stubbornly dirty skin on their overweight child is actually acanthosis nigricans, a symptom of insulin resistance.
另一个关键观察是骨骼肌胰岛素抵抗在肝脏细胞胰岛素抵抗发生之前，并且脂肪产物在肝脏中增加了。
Another key observation was that skeletal muscle insulin resistance precedes the development of insulin resistance in liver cells, and that fat production in the liver is increased.
大量研究表明胰岛素抵抗与多种疾病有着密切的关系，因此胰岛素抵抗被认为是当今影响人体健康的最主要代谢性疾病。
It shows that many diseases relate to the insulin resistance in the most research, so the insulin resistance has been considered as the most important factor of people's metabolism diseases.
研究表明，仅仅是为期一周的睡眠不足就会造成新陈代谢紊乱，尤其是会干扰身体分解葡萄糖的能力，导致胰岛素抵抗。
Research shows that just a week of sleep deprivation can mess with metabolism, specifically interfering with the body's ability to process glucose and leading to insulin resistance.
胰岛素抵抗是身体对于调节糖类能量摄入的基本激素胰岛素停止作出反应。
Insulin resistance occurs when the body ceases to respond to insulin, the essential hormone that regulates the take-up of sugar energy sources.
胰岛素抵抗是这些肿瘤发病的重要病理生理学基础之一。
Insulin resistance is one of the important pathophysiological basis of these malignant tumors.
结论：瘦素和糖尿病之间的关联是通过胰岛素抵抗介导的。
CONCLUSIONS: The association between leptin and incident diabetes is mediated by insulin resistance.
因此，胰岛素抵抗是2型糖尿病致动脉粥样硬化的潜在病因。
Therefore, insulin resistance is believed to constitute the underlying cause of atherosclerosis in type 2 diabetes.
越来越多的研究提示，胰岛素抵抗和2型糖尿病是一个慢性非特异性炎症过程。
Numerous studies have suggested that type 2 diabetes and insulin resistance are one kind of chronic inflammation.
越来越多的研究提示，胰岛素抵抗和2型糖尿病是一个慢性非特异性炎症过程。
Numerous studies have suggested that type 2 diabetes and insulin resistance are one kind of chronic inflammation.
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