目的：研究脑创宁对闭合性脑外伤模型小鼠血脑屏障的保护作用。
Objective: To research the protective effects of Naochuangning on blood brain barrier in closed cerebral trauma mice.
结果：脑创宁可明显减轻模型小鼠脑水肿程度，降低伊文思蓝含量，保护血脑屏障。
Result:Naochuangning could obviously lessen the level of cerebral edema and cut down the content of Evans blue and protect the blood brain barrier.
目的：比较两种不同体外血脑屏障(BBB)模型的功能差异。
Aim: To compare the functional difference between two kinds of blood-brain -barrier (BBB) models in vitro.
目的：建立药物透过血脑屏障的三维构效模型，为药物分子设计提供理论依据。
AIM: To construct 3d QSAR models of drugs passing through the blood brain barrier (BBB), that provide a theoretical basis for molecular drug design.
同时他还说：“这个研究结果强调了这样一个事实——血脑屏障的通透性改变是发生象实验性变应性脑脊髓炎(一种多发性硬化病的动物模型)这类中枢神经系统感染性疾病的重要因素。”
"This puts an emphasis on the fact that blood brain permeability changes are an important aspect of the development of a CNS inflammatory disease like EAE, an animal model of MS," he says.
一个人类血脑屏障细胞培养3d新模型将被用来拍摄纳米微粒和大脑之间最初的互动。
A new, living 3d cell-culture model of the human blood-brain barrier will be used to screen the interaction initially between the nanoparticles and the brain.
结果与对照组比较，模型组小鼠海马神经细胞出现线粒体和突触损伤，血脑屏障结构异常。
Results The ultrastructure in the brain of mice in transgenic group had pathological changes compared with negative group.
因此，HB-1细胞将是阐明形成血脑屏障的内皮细胞上的附贴分子和选择性地让特殊细胞侵入脑的一个很好的模型。
On the base of the observation, we expect that the HB-1 cell could be used as a very useful model to elucidate the mechanism of infiltrating the blood-brain barrier for certain type of cells.
因此，HB-1细胞将是阐明形成血脑屏障的内皮细胞上的附贴分子和选择性地让特殊细胞侵入脑的一个很好的模型。
On the base of the observation, we expect that the HB-1 cell could be used as a very useful model to elucidate the mechanism of infiltrating the blood-brain barrier for certain type of cells.
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