This represents a sea change in pharmaceutical policies.
这代表着制药政策上的巨大变化。
One central issue is whether the fall of the mighty is a cycle or a sea change.
一个关键问题是，这场强者的衰颓是一个周期还是一场巨变。
"It is a sea change in the way the industry works, " says Omar Tawakol, CEO of BlueKai.
这是行业工作模式的彻底性改变。
That may mark a sea change in social attitudes but it could equally be, pace Mr Schmidt, transient.
这可能标志着社会看法的重大转变，但也完全可能——借施密特所言——是短暂现象。
Only content from accounts marked public will be indexed by Bing, but it's a sea change none the less.
只有标记为公开账户的内容才会被Bing收录，但是这个变化已经很重要了。
Shopping habits shape cities and reflect culture, and a sea change has occurred in how Americans try to buy.
购物习惯塑造城市，折射文化，美国人的购物习惯已经发生巨大变化。
The past decade has resulted in a sea change in many countries that is often misunderstood (or just invisible).
过去的十年造成了许多国家天翻地覆的巨变，这点常被误解（或直接无视）。
The Prime Minister is convinced that there will soon be a sea change in the relations between the two countries.
首相相信两国间的关系不久将会有根本的变化。
Current therapies are powerful but with unintended targets and side effects that can be equivalent to a sea change.
现在的治疗方法虽然作用很强，但是没有特定的靶向，因而会产生同等程度的副作用，就像海浪一样。
But there are those under the impression that this will mean a sea change in the world's linguistic terrain as well.
但有些人的印象是，这将意味着世界语言形势发生剧变。
When Mr Gourevitch went back to Rwanda last year for the first time in a decade, he found it had undergone a sea change.
去年，当Gourevitch先生在过去10年里第一次返回卢旺达时，他发现那里已经经历了沧海桑田的变化。
THE rapid international rise of companies such as Samsung Electronics and LGE underlines a sea change in South Korea’s chaebol in just a decade.
诸如三星电子、LG电器等公司在国际上的迅速成长深刻揭示了十年来韩国财团发生的巨大变化。
You described Linked data as a sea change akin to the invention of the WWW itself - i.e. we've gone from a Web of documents to a Web of data.
你认为关联数据像万维网的发明那么重要。
THE rapid international rise of companies such as Samsung Electronics and LGE underlines a sea change in South Korea's chaebol in just a decade.
诸如三星电子、LG电器等公司在国际上的迅速成长深刻揭示了十年来韩国财团发生的巨大变化。
He said that Linked data was a sea change akin to the invention of the WWW itself. We've gone from a Web of documents, via the WWW, to a Web of data.
他说关联数据是和万维网的发明一样的巨大变革，我们正在通过万维网从文件互联网走向数据互联网。
More important, the perfect storm of the past 18 months has seared the American consumer psyche, likely launching a sea change in spending behavior.
更重要的是，过去18个月的完美风暴沉重打击了美国消费者的信心，因而很可能令其支出行为发生巨大变化。
We think this crisis has already begun to trigger a sea change in consumer spending behavior, as consumers now embark on a long period of rebuilding thrift.
我们认为，由于本次危机的打击，美国消费者的支出行为已经开始发生重大转变，漫长的节俭支出时期已经开始。
For one can fairly say that ties between the two sides have undergone a sea change in recent years and Taiwan's economic future is now bound closely to the Mainland.
可以说在过去几年来，两岸的关系已经发生了质变，台湾的经济前途，已经和大陆密切相关。
One is quite usual, a month of ambition, pressure, career and prestige involvements. All these are undergoing a sea change now to 2024, as Thursday to Saturday will show.
其中一件非常普通，即为迎来代表抱负，压力，事业与声望的新的一个月，从现在到2024年，以上各方面将面临天翻地覆的变化，而周四至周六即可有所见证。
Whether album number three beckons a sea change into unchartered waters remains to be seen, but for now Vampire Weekend’s status as fine purveyors of guitar-orientated pop is firmly cemented.
第三张专辑他们会否有彻底的转变还不得而知，不过眼下乐队作为吉他流行曲供应 者的地位是得到加强了。
A recently published study of online research habits, conducted by scholars from University College London, suggests that we may well be in the midst of a sea change in the way we read and think.
伦敦大学学院的学者引领的一项关于在线搜索习惯的研究最近获得发表。该研究指出，我们可能已经彻底置身于阅读与思考方式的巨变之中。
Although initially appealing, the hypothesis of a simple climatic change related to sea levels is insufficient to explain all the data.
与海平面相关的简单气候变化假说虽然起初很吸引人，却不足以解释所有的数据。
Sea level rise is expected as a consequence of continuing climate change, which is spurred by human activities including the burning of fossil fuels.
海平面上升是持续不断气候变化导致的结果，是由人类活动诱发的，包括燃烧矿物燃料。
"We are without a doubt in the midst of an extraordinary sea change," she told me. "the transformation is momentous-immensely liberating and immensely scary."
“毫无疑问，我们正置身于一场非凡的翻天覆地的变化之中，”她告诉我，“这是重大的转变，带来极大解放的同时又让人不免惶恐。”
"We are without a doubt in the midst of an extraordinary sea change," she told me. "the transformation is momentous-immensely liberating and immensely scary."
“毫无疑问，我们正置身于一场非凡的翻天覆地的变化之中，”她告诉我，“这是重大的转变，带来极大解放的同时又让人不免惶恐。”
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