Mice with a rodent equivalent of the disease showed a 50 per cent reduction in levels of amyloid protein in their brains after the scientists added caffeine to their drinking water.
把疾病基因移植到鼠类身上,科学家发现当把咖啡因注入到老鼠饮用的水中,这些老鼠脑内的淀粉状蛋白指数会减少50%。
They alter the way it cleaves amyloid precursor protein.
它们改变了这个酶切割淀粉样蛋白前体的方式。
Amyloid is an abnormal protein usually produced by cells in your bone marrow that can be deposited in any tissue or organ.
淀粉样蛋白通常由骨髓细胞合成,可以在各个组织和器官中沉积。
The study sheds light on how insulin interacts with amyloid, a toxic protein found in Alzheimer's.
这项研究揭示了阿尔兹·海默病患者中发现的淀粉和胰岛素怎样互相作用。
Initially the amyloid appears as a long protein that is then cut by enzymes into shorter fragments that become molecularly sticky and clump together, forming a plaque.
刚开始,类乙型蛋白以长条状的形式出现,接著被一种酵素分解为分子般黏状的细小碎片,然后纠结在一起,形成了所谓的“病灶”。
The gene is also involved in removing clumps of rogue protein known as amyloid plaques, which are commonly seen in the brains of Alzheimer's patients.
该基因还参与消除常见于老年痴呆症大脑中称为类淀粉斑(amyloid plaques)的恶性淀粉蛋白凝块。
Doctors are also beginning to use new technology to detect amyloid, a plaque-causing protein that can lead to Alzheimer's disease.
博士们正在用新的技术来检测淀粉样蛋白,它是一个可以引起斑块的蛋白导致阿尔茨海默病。
People with the disease get plaques in their brains made up of a small protein called amyloid-beta, which clumps together and disrupts brain signals.
得了这种病的人大脑里面的血小板形成一种叫做淀粉样蛋白的蛋白质,这种蛋白质聚集在一起打乱了大脑发出的信号。
Amyloid plaques form when a molecule called amyloid precursor protein (APP) is chopped up by two enzymes known as beta-secretase and gamma-secretase.
当一种叫淀粉样前体蛋白(APP)的分子被两种酶——分别叫作贝塔-分泌酶和伽玛-分泌酶——切断时就形成了淀粉样斑块。
A key aspect of Alzheimer's is sticky clumps of an abnormal protein in the brain called beta amyloid plaques.
阿尔兹·海默氏症主要是由于脑部聚集结块的异常蛋白质,名为be ta淀粉状蛋白斑。
He has tested it so far in mice, and found the animals have better memory and other cognitive skills and fewer clumps of beta-amyloid and tau protein.
目前的实验对象为老鼠。他还发现动物具有更强的记忆力和其他认知能力,更少的贝塔淀粉样和tau蛋白质凝结。
It contains antibodies against a protein called beta-amyloid, which many Alzheimer's researchers believe plays a pivotal role in the progression of the disease.
它包含能够对抗一种淀粉样蛋白(beta - amyloid)的抗体,许多阿滋海默症研究者都认为这种淀粉样蛋白在疾病的形成中扮演了关键的角色。
Traditional drug development in Alzheimer's disease is taking too narrow an approach by focusing intensively on the buildup of amyloid beta-protein in the brain, Dr. Nixon says.
传统的治疗老年痴呆症的药物研发思路仅仅集中在淀粉样β蛋白的累积上,Nixon博士说。
The causes for Alzheimer's disease are not known, but dysregulation of amyloid-precursor protein expression and beta-amyloid clearance is hypothesized (beta-amyloid cascade).
虽然导致老年痴呆症的原因还没有发现,但是有人假设其原因是淀粉样前提蛋白的调节异常和β-淀粉样蛋白的消失(β-淀粉样蛋白连锁反应)。
The amyloid which occurs in certain endocrine glands is designated AE protein.
出现在内分泌腺上的淀粉样蛋白是特定的AE蛋白。
Objective To investigate the expression of glial fibrillary acidic protein(GFAP) in brains of patients with cerebral amyloid angiopathy(CAA) related to hemorrhage.
目的研究胶质纤维酸性蛋白(GFAP)在淀粉样脑血管病(CAA)患者脑组织的表达。
Aim: To investigate the changes of amyloid precursor protein (APP) transcriptional level at different ischemic times in rats' ischemic penumbra and core of cortices.
目的:研究大鼠局灶性脑缺血不同缺血时间皮质半暗带和中心区淀粉样前体蛋白(APP)在转录水平表达规律。
Amyloid beta is best known as the protein that forms the giant plaques that riddle the brains of people with Alzheimer's.
众所周知? -淀粉样蛋白导致老年痴呆症患者的大脑里面形成巨大的斑块。这些斑块含有数十亿的。
Amyloid precursor protein (APP) has been known to act as an important protein during the occurrence of Alzheimer's disease (AD).
淀粉样前体蛋白(APP)是阿尔茨海默氏病(AD)发病过程中有重要作用的蛋白。
One of the most promising is to inhibit an enzyme that shears off amyloid beta from a larger protein.
最优希望的一种就是抑制一种将β淀粉状蛋白从大蛋白中剪切下来的酶。
We concluded that a protein with high molecular weight such as BSA can also form amyloid fibrils, although the resultant amyloids showed no cytotoxicity due mainly to their low surface hydrophobicity.
为此我们得出结论:高分子量蛋白如bsa也能形成淀粉样纤维,但是BSA形成的淀粉样纤维主要因为其表面疏水性较低使其没有细胞毒性。
Mice with a rodent equivalent of the disease showed a 50% reduction in levels of amyloid protein in their brains after scientists spiked their drinking water with caffeine.
老鼠以及与该疾病相当的啮齿类动物,在科学家们向牠们掺入含有咖啡因的标准饮用水之后,在牠们的大脑中显示出淀粉样蛋白质水平50%的减少。
Both transcription and translation of rat serum amyloid a protein were studied by using in vitro systems.
我们使用体外系统研究了大鼠血清淀粉样a蛋白的转录和转译。
In recent years, a number of diseases are believed to be caused by amyloid deposition results from protein misfolding.
近年来研究发现,蛋白质的错误折叠可以形成淀粉样沉积进而导致一些疾病的产生。
Objective To investigate the serum levels of C-reactive protein(CRP) and amyloid a(SAA) in patients with unstable angina pectoris(UAP) and acute myocardial infarction(AMI).
目的:检测C-反应蛋白(CRP)与血清淀粉样蛋白(SAA)的水平并分析它们与急性心肌梗死(AMI)及不稳定性心绞痛(UAP)的关系。
Conclusion the amyloid protein may be derived from the apoptotic keratinocytes.
结论淀粉样蛋白可能来源于凋亡的角质形成细胞。
When the amyloid protein is made up of immunoglobulin light chains, then it is "AL amyloid" and when it is derived from serum amyloid-associated protein, then it is "AA amyloid.
当淀粉样蛋白由免疫球蛋白轻链组成时,那么它就是“免疫细胞衍生性淀粉样变性”,当它来自于血清淀粉相关蛋白时,就是“反应性系统性淀粉样变性”。
Mutations in the gene encoding the human amyloid precursor protein (APP) cause familial AD, but there is not yet a clear understanding of the normal functions of APP family of proteins in neurons.
淀粉样肽前体蛋白(APP)基因突变导致家族性ad,但到目前还没有对APP家族蛋白正常功能的清楚认识。
Mutations in the gene encoding the human amyloid precursor protein (APP) cause familial AD, but there is not yet a clear understanding of the normal functions of APP family of proteins in neurons.
淀粉样肽前体蛋白(APP)基因突变导致家族性ad,但到目前还没有对APP家族蛋白正常功能的清楚认识。
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