The results showed that percutaneous fluxes of 1 in pH7.4 phosphate buffer solution with anodal and cathodal iontophoresis were 230% and 45% of that of the passive diffusion flux respectively.
结果表明,1生理盐水饱和液阳极导入时的透皮速率是被动扩散的2.3倍,阴极导入时药物的透皮速率是其被动扩散的45%,说明电渗作用明显促进了分子型药物1的经皮渗透;
The results showed that percutaneous fluxes of 1 in pH7.4 phosphate buffer solution with anodal and cathodal iontophoresis were 230% and 45% of that of the passive diffusion flux respectively.
结果表明,1生理盐水饱和液阳极导入时的透皮速率是被动扩散的2.3倍,阴极导入时药物的透皮速率是其被动扩散的45%,说明电渗作用明显促进了分子型药物1的经皮渗透;
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