RESULTS: 6 compounds showed anticonvulsant activity.
结果：有6个化合物具有抗惊厥活性。
Levetiracetam is an antiepileptic drug with novel antiepileptic mechanism, in which binding to SV2A, a synaptic vesicle protein, may result in its anticonvulsant activity.
左乙拉西坦是一种新型作用机制的抗癫癎药物，其抗癎机制可能是通过影响突触囊泡蛋白SV2A来实现。
Objective To study if calmodulin antagonist has anticonvulsant activity, and to provide theoretical evidence for exploring new anticonvulsant drug to improve clinical epilepsy therapy.
目的了解钙调素拮抗剂有无抗痫作用，为临床上开发新型的抗痫药以进一步控制癫痫提供理论依据。
Aim To study the role of nitric oxide by measuring the expression and activity of nitric oxide synthase in hippocampus of rats tolerance and dependence to the anticonvulsant action of flurazepam.
目的通过测定大鼠对氟西泮抗痫耐受性和依赖性时海马中一氧化氮合酶（NOS）蛋白表达及活性的变化，探讨一氧化氮（NO）在此过程中可能的作用。方法建立大鼠对氟西泮抗痫耐受性和依赖性的模型。
Aim To study the role of nitric oxide by measuring the expression and activity of nitric oxide synthase in hippocampus of rats tolerance and dependence to the anticonvulsant action of flurazepam.
目的通过测定大鼠对氟西泮抗痫耐受性和依赖性时海马中一氧化氮合酶（NOS）蛋白表达及活性的变化，探讨一氧化氮（NO）在此过程中可能的作用。方法建立大鼠对氟西泮抗痫耐受性和依赖性的模型。
应用推荐