My aim to write this message is to clarify some scientific issues about cancer stem cell here.
我发此贴的目的是想澄清有关“癌症干细胞”的若干科学问题。
Objective To study the correlation of breast cancer stem cell with relapse of breast cancer after chemotherapy.
目的探讨乳腺癌干细胞与乳腺癌化疗失败的相关性。
The interaction between fibroblast growth factor and its cancer stem cell surface receptor may play the important role.
其中成纤维细胞生长因子与其在癌症干细胞表面受体之间的互动可能起重要的作用。
My project is focus on the cancer stem cell research when I worked in University of Michigan as an Assistant Professor.
在密西根大学工作至今，一直从事肿瘤及肿瘤干细胞的研究。
This review described the recent progress in cancer stem cell research as well as many problems that remained to be solved.
本文就癌干细胞在这方面的研究进展及存在的问题作一综述。
Title: Human breast cancer stem cell markers CD44 and CD24: enriching for cells with functional properties in mice or in man?
题目人乳腺癌干细胞标记分子CD44和CD24：富含了具有功能特征的人或者小鼠的细胞？
The cancer stem cell hypothesis posits that tumors are derived from a single cancer-initiating cell with stem cell properties.
肿瘤干细胞学说表明肿瘤由一个具有干细胞特征的肿瘤始祖细胞分化而来。
Researchers found that breast cancer stem cells are regulated by a type of cell derived from bone marrow, called mesenchymal stem cells.
研究人员发现，间质干细胞（来源于骨髓）调控着乳腺癌干细胞。
At the same time, more and more studies have suggested that epigenetic regulation may play important roles in cancer stem cell development.
与此同时，越来越多的研究表明，对于肿瘤干细胞的发生与功能维持，表观遗传学的调控机制可能发挥着极其重要的作用。
The research on isolation and identification of lung cancer stem cell markers will provide a new strategy for the treatment of lung cancer.
但肿瘤干细胞学说的创立与研究使肺癌的根治成为了可能，现就目前肺癌干细胞标志物的研究进展作一系统性总结。
Objective To know if MCF-7 breast cancer cell line has breast cancer stem cell, and change of stem cell pool in diverse incubation circumstance.
目的了解乳腺癌细胞系mcf - 7中是否存在乳腺癌干细胞，以及在不同的培养条件下，干细胞池的变化情况。
Stem cell research has greatly contributed to the field of oncology with the identification and isolation of cancer stem cells from a variety of tumors.
干细胞研究极大地促成了肿瘤学另一个新领域的研究，即从各种肿瘤中分离并鉴定肿瘤干细胞。
These findings suggest that this cancer stem cell gene signature may be used to identify patients at the highest risk for disease recurrence and metastasis.
这些发现表明肿瘤干细胞基因标签可用于鉴别具有高复发和转移风险的患者。
Similar cancer stem cells have been previously identified in leukemia and breast cancer and in cell lines of central nervous system and gastrointestinal tumors.
类似的癌症干细胞早前在白血病、乳癌、中枢神经系统细胞株和胃肠道肿瘤中鉴定出。
In this review we present scientific evidence supporting the cancer stem cell model of tumor progression, and discuss the experimental and therapeutic implications.
本文综述具有科学证据支持并与肿瘤进展相关的肿瘤干细胞模型，同时探讨该模型的在实验应用和临床治疗的价值。
By blocking these cytokine signals, researchers hope that they can successfully target the cancer stem cell population providing a more effective treatment for breast cancer.
阻断这些细胞因子信号，研究人员希望能通过靶向肿瘤干细胞群，成功地提供一种更有效的乳腺癌治疗手段。
That signaling pathways such as Bmi1 and Wnt have similar effects in normal and cancer stem cell self-renewal suggests that common molecular pathways regulate both populations.
bmi1和wnt等信号信号通路在正常及肿瘤干细胞的自我更新中有类似的效果提示这一共同的分子途径可以调节两者的作用。
The cancer stem cell hypothesis says that tumors originate in a small number of cells, called cancer stem cells, and that these cells are responsible for fueling a tumor's growth.
癌症干细胞假说—癌症起源于很小数量的被称为癌症干细胞的细胞，这些细胞为癌症的生长提供能量。
The theory of cancer stem cell proposes that the tumor tissue has its own cancer stem cells in it and regards cancer stem cell as the key to regeneration, metastasis and recurrence.
肿瘤干细胞学说认为，肿瘤组织中也存在少量具有干细胞性质的肿瘤干细胞，肿瘤干细胞是肿瘤发生、转移和复发的关键。
Objective:To prepare functional monoclonal antibodies(McAbs) against liver cancer stem cells, so as to provide candidate antibody drugs for stem cell-targeted therapy of liver cancer.
摘 要?目的：研制抗肝癌干细胞的功能性单克隆抗体，为肝癌干细胞的靶向治疗提供候选抗体药物。
They found Herceptin reduced the number of cancer stem cells in the HER2-positive breast cancer cell lines by 80 percent, dropping it to the same levels seen in HER2-negative cell lines.
他们发现赫赛汀减少HER 2阳性乳腺癌症细胞系数量的80%，降至与her 2阴性细胞系相同的水平。
The upshot of all this is that the stem-cell hypothesis of cancer growth looks a good one.
所有这些所导致的结果就是关于癌症干细胞观于癌症扩散的假设看上去前景光明。
Sipkins said it appears the cancer overproduces a normally expressed molecule called a stem cell factor, which entices normal stem cells into the cancer niche.
斯普金思说，看来癌细胞大量产生一种以正常方式传送的分子，名为干细胞因子，这种分子会引诱正常干细胞到癌细胞的处所。
The molecule delivers proteins to a crucial cluster of genes and helps regulate immune response, cancer growth, and fat and stem-cell production, among other things.
这种LINCs（RNA）将蛋白质运输到一个关键基因簇，并帮助细胞控制管理诸如免疫反应，肿瘤生长，肥胖细胞及干细胞的生成等事务。
After dialysis helped his kidneys recover, it was time to attack the cancer, and in February 2009 he underwent chemotherapy and a stem cell transplant.
当透析使他的肾功能恢复正常后，他开始对抗癌症，并且在2009年的2月他去做了化疗和干细胞移植。
Wiebicke underwent an experimental stem cell transplant procedure last summer, when his cancer was in remission.
去年夏天，当他的癌症在缓解的时候，韦比克进行了实验性的干细胞移植手术。
Using stem cell technology, reproductive scientists in Texas, led by Dr. Richard r. Berhringer at the M.D. Anderson Cancer Center, have produced male and female mice from two fathers.
使用干细胞技术，由richardr. Berhringer博士带领的德克萨斯州M.D.A nderson肿瘤中心的生殖科学家们利用两只公鼠成功繁殖出雌性和雄性老鼠后代。
Using stem cell technology, reproductive scientists in Texas, led by Dr. Richard r. Berhringer at the M.D. Anderson Cancer Center, have produced male and female mice from two fathers.
使用干细胞技术，由richardr. Berhringer博士带领的德克萨斯州M.D.A nderson肿瘤中心的生殖科学家们利用两只公鼠成功繁殖出雌性和雄性老鼠后代。
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