Objective To construct a bivalent VP1 gene vaccine against Coxsackie virus B1 and B3 (CVB1 and CVB3) and to test its immunogenicity in mice.

目的构建柯萨奇病毒（CV）B1/B3型二价VP1基因免疫质粒，并探讨其免疫原性。

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HN is a common virus, Coxsackie virus, other parts may cause respiratory tract infections.

HN病毒是一种常见病毒，会引起呼吸道等部位感染。

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Through the experimental study confirmed that Shuxin Capsule on Coxsackie B3 virus caused by myocarditis can play a good role in the treatment and prevention, have a direct myocardial protection.

通过实验研究证实，舒心胶囊对柯萨奇B_3病毒引起的心肌炎能够起到很好的治疗和预防作用，对于心肌有直接的保护作用。

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Through the experimental study confirmed that Shuxin Capsule on Coxsackie B3 virus caused by myocarditis can play a good role in the treatment and prevention, have a direct myocardial protection.

通过实验研究证实，舒心胶囊对柯萨奇B_3病毒引起的心肌炎能够起到很好的治疗和预防作用，对于心肌有直接的保护作用。

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