Cytochrome P450 is one of the most versatile enzymes in nature.
细胞色素P 450酶是自然界中最万能的生物酶之一。
Cytochrome P450 enzyme are an important enzyme family in drug metabolism.
色素氧化酶p 450是药物代谢中的一个重要的酶系。
Objective:To study activity of cytochrome P450 for human liver microsomes.
目的：为测定人肝细胞微粒体细胞色素P450氧化酶的活性。
The progress on the relationship between cytochrome P450 and drug-induced liver injury was reviewed.
主要介绍细胞色素P450与药物性肝损伤的相关研究进展。
Cytochrome P450 3a (CYP3A) is one of the key isoenzymes involved in the metabolism of clinical drugs.
细胞色素P 4503A (CYP3A)是参与临床药物代谢的主要CYP同工酶之一。
OBJECTIVE to introduce the research status of cytochrome P450 and its new applications in clinical pharmacy.
目的介绍细胞色素P 450的研究进展及其在临床药学工作实践中的指导意义。
Objective To determine the distribution of cytochrome P450 1A1(CYP1A1) gene polymorphisms in Guangdong Hans women.
目的探讨广东汉族妇女细胞色素P45 01A1（CYP1A1）基因的多态性分布规律。
An example of a flavoprotein undergoing a one-electron transfer is with the microsomal NADPH-cytochrome P450 reductase.
的一个经历一个单电子转移黄素蛋白的例子是与微粒NADPH-细胞色素P 450还原酶。
For many years, researches on Cytochrome P450 had been focused on their roles in exogenous drugs and poisons metabolism.
多年来，对细胞色素酶P 4 5 0的研究主要集中在其代谢外源性药物和毒物的方面。
Aging related changes have been evaluated in hepatic cytochrome P450 content in rats by specific cytochrome P450 enzymes.
大鼠肝细胞色素P 450含量与年龄相关的变化是由特异的细胞色素P 450酶引起的。
Conclusion The K39 in HO has important effects on accepting and transporting electrons from NADPH-cytochrome P450 reductase.
结论HO的碱性氨基酸K39在接受并传递NADPH-细胞色素P450所提供的电子时具有重要作用。
Cytochrome P450 and GST are two important complex gene families of enzymes that metabolize therapeutic drugs and carcinogens.
细胞色素P 450和谷胱甘肽s转移酶是二组参于抗肿瘤药物和致癌剂代谢的重要酶系。
In conclusion, levofloxacin significantly inhibited metabolism of metoprolol in the cytochrome P450 of rat hepatic microsomes.
结论：左氧氟沙星可抑制大鼠肝微粒体细胞色素P 45 0系统对美托洛尔的代谢。
Study in Electrochemistry of Cytochrome P450 is a Profile of the effort in order to use Cytochrome P450 as catalyst in industry.
细胞色素P 450的电化学研究从一个侧面反映了为使细胞色素P 450达到工业催化剂的最终目的人们所作的不懈努力。
Cytochrome P450 (CYP450) is the crucial metabolizing enzymes in the bodies. It is the most important effect for drug metabolization.
细胞色素P 450 (CYP450)是机体药物代谢的关键酶，在药物生物转化中起着重要作用。
The present drug2013drug interaction can be attributed to a strong inhibitory effect on cytochrome P450-3A4 activity by voriconazole.
究其原因，是因为伏立康唑对细胞色素P450-3A4活性有强大的抑制作用。
In recent years, researches found that there were many kinds of cytochrome P450 enzymes which related to multidrug resistance of tumor.
目前的研究发现，有多类细胞色素P 450酶与肿瘤多药耐药的发生密切相关。
AIM: to investigate the interventional effect of cytochrome P450-CYP2J3 gene on hypertension and insulin resistance induced by fructose.
目的：观察细胞色素P 450 -CYP2J3基因对果糖诱导的高血压和胰岛素抵抗的干预作用。
Objective to introduce the research status of cytochrome P450 and its new applications in the study of toxicity and new drug evaluation.
目的介绍细胞色素P 450的研究进展及其在毒理学和药物评价方面的应用。
This review provides a better understanding of the cytochrome P450 system with a focus on those enzymes most involved in drug metabolism.
这次综述提供了一个对大多数药物代谢有关的酶为重点的细胞色素P 450系统的了解。
The results implied that the change of GAS modulated by the cytochrome P450 monooxygenase genes might influence the columnar growth habit.
由此推断，由细胞色素P 450单加氧酶基因所调控的赤霉素gas变化影响了苹果柱型性状的表达。
Objective: to study the effects of trans-resveratrol and trans-piceid on liver weight, contents of microsomal protein and cytochrome P450.
目的：研究反式白藜芦醇及反式白藜芦醇苷对大鼠肝质量、肝微粒体蛋白质及细胞色素P 450的影响。
Epilepsy is a common disease in nervous system. Most antiepileptic drugs are metabolized by liver enzymes. such as cytochrome P450 enzyme.
癫（癎）是危害人类健康的常见神经系统疾病，临床常用抗癫（癎）药多通过细胞色素P450等肝药酶代谢。
Azole and triazole drugs are cytochrome P450 inhibitors widely used as fungal antibiotics and possessing potent antimycobacterial activity.
唑类和三氮唑类药物作为细胞色素P 450抑制剂广泛被作为抗真菌药物和抗微生物药物使用。
Objective: to investigate the effects of the ethyl acetate extract of Semen Hoveniae capsule on liver microsomal cytochrome P450 system in rats.
目的：观察枳煿子乙酸乙酯提取物胶囊对大鼠肝微粒体细胞色素P 450及其同工酶的影响。
Those results lay the foundations of clarifying the relation between cytochrome P450 aromatase gene and the mechanism of ESD to a certain extent.
这些结果为揭示细胞色素P 450芳香化酶基因与环境性别决定机制的关系奠定了基础。
Among such Cytochrome P450 enzymes, CYP2J2 mainly metabolizing arachidonic acids into epoxyeicosatrienoic acids, was detected recently in human beings.
CYP2J就是这样一种主要代谢内源性物质花生四烯酸的细胞色素酶P4 5 0超家族。
Objective to construct the expression vectors of human cytochrome P450 (CYP) 4f2 wild type, V81G and V433M Variants and express and purify CYP4F2 protein in e.
目的构建人细胞色素P450 4f 2基因野生型、V81G和V433 M突变型表达载体，在大肠杆菌中表达并纯化出CYP4F2蛋白。
In normal groups, the cytochrome P450 content and the NADPH cytochrome P450 reductase activity of A. ypsilon were significantly higher than that of M. separata .
结果表明，对照组小地老虎中肠细胞色素P4 5 0含量及NADPH-细胞色素P4 5 0还原酶活性均显著高于粘虫。
The AuNPs and its labeled Cytochrome P450 were observed by the UV-visible light absorption spectrum, transmission electron microscopy (TEM) and fluorescence spectrum.
用紫外-可见吸收光谱仪、投射电子显微镜以及荧光光谱仪，研究纳米金及其标记细胞色素P450的光谱性质。
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