Deinococcus radiodurans, as a model organism in DNA damage and repair, is the most resistant bacterium to ionizing radiation.
耐辐射奇球菌作为DNA损伤和修复的典范生物,是对电离辐射最有抵抗力的细菌。
If the cell then botches the repair, stitching the fragments back together in a 'higgledy piggledy' fashion, the damage to its cache of DNA, leaves it ripe for the rapid development of cancer.
如果这个细胞开始笨拙地修补,把碎片杂乱的缝合起来,这样就破坏了原来的DNA结构,为癌症的快速形成提供了条件。
Shock waves create energetic subatomic particles called cosmic rays, which can tear apart biomolecules and damage DNA beyond repair.
冲击波创造出一种叫做宇宙射线的高能亚原子微粒,这东西会撕裂生物分子并对DNA造成无法修复的损伤。
The results confirmed that the alcohol (ethanol) was being converted to acetaldehyde, causing DNA damage and switching on the cell's DNA repair genes.
结果表明,酒精(乙醇)转换成乙醛后破坏dna,激活细胞内dna的修复基因。
Normally zebrafish, which carry the same p53 gene as humans, can survive low doses of radiation, which causes damage to the DNA, because the gene steps in to repair that damage.
在通常情况下,像人类一样携带相同p 53基因的斑马鱼可以承受小剂量的放射,放射会对DNA造成损坏,而基因会加入对损坏的修复。
There also exists a cytosolic fumarase isoenzyme that is involved in DNA damage repair (3).
存在细胞质延胡索酸水合酶的同工酶,参与DNA损伤的修复(3)。
DNA repair is essential for the accurate preservation of genetic information and to ensure the healthy functioning of cells, and a connection between aging and DNA damage has long been suspected.
DNA修复对遗传信息的准确保存和确保细胞的正常功能是必需的,年龄和DNA损伤的关系一直存在疑问。
The ubiquitin-conjugating pathway involves in numerous metabolic processes in cells, including DNA damage repair, cell cycle control, stress responses and so on.
泛素缀合途径参与细胞的多种代谢过程,包括DNA损伤修复、细胞周期调控及应激反应等。
Objective to study the DNA damage and repair of normal lung interstitial cells and human lung adenocarcinoma cells exposed to cigarette smoke.
目的探讨经香烟烟雾溶液染毒的人正常肺间质细胞和人肺腺癌细胞的DNA损伤及其修复效应。
The single cell gel electrophoresis assay is a method that can inspect the DNA damage and repair of cells which have nucleus.
单细胞凝胶电泳技术是一种在单细胞水平上检测有核细胞DNA损伤与修复的方法。
Micronucleus rate, DNA damage and repair were detected by micronucleus test in vitro and single cell gel electrophoresis(assay).
体外微核试验及单细胞凝胶电泳检测两种细胞微核率及DNA损伤与修复的差异。
The DNA oxidative damage is believed that it is repaired mainly by the base excision repair (BER) mechanism with many repairing enzymes.
已知细胞中DNA氧化性损伤主要通过碱基切除修复(BER)来完成,许多修复酶参与了这一修复过程。
ObjectiveTo study the reaction of Guizhou miniature pig to the DNA damage and repair caused by chemical substances or drugs.
目的研究贵州小型猪淋巴细胞对化学物或药物引起的DNA损伤及修复影响的反应。
Conclusions Some DNA replication, and damage repair genes associated with benzene poisoning show differential expression, which provides the basis for screening biomarkers of benzene poisoning.
结论苯中毒患者外周血白细胞的DNA复制及损伤修复基因与正常人相比存在差异性表达,为进一步筛选苯中毒生物标志物提供了依据。
In response to DNA damage, the complex cellular mechanisms including cell cycle arrest, transcription induction and DNA repair are activated.
为了应对DNA损伤,细胞有一套复杂的机制,包括细胞周期停滞,诱导转录和DNA修复被激活。
Purpose and methods: Single cell gel electrophoresis (SCGE), sister chromatid exchanges (SCE), chromosome aberrations are three methods to determine DNA damage and repair.
目的与方法:单细胞凝胶电泳技术(SCGE)、姐妹染色单体交换法(SCE)和染色体畸变分析法均能被用来检测dna的损伤或修复。
Objective To screen DNA replication, and damage repair genes associated with benzene poisoning by using gene expression profile analysis.
目的筛选与苯中毒有关的DNA复制及损伤修复基因。
Looking at cells in a dish, the team found that mistakes in these genes prevented the cells from being able to repair damage to their DNA.
研究团队调查研究一个盘子里的细胞,发现这些基因的缺陷能够阻止细胞修复对它们DNA的损害。
In this study, researchers exposed lightly and darkly pigmented human melanocytes to UVA radiation and assessed DNA damage and the capacity of these cells to repair damaged DNA.
在该研究中,研究人员分别将含有少量和多辆色素的人黑色素细胞置于uva辐射中,并评价DNA损伤以及这些细胞修复损伤dna的能力。
It is suggested that mammal an organism has a marked physiological compensation, regeneration and repair activity for DNA damage.
抑制作用特点:迅速、严重、恢复迅速,且有超常水平,提示动物机体对DNA烃化损伤具有较强的代偿、再生和修复能力。
PARP1 is an enzyme that is one of the "first responders" to DNA damage and is involved in several DNA repair machineries.
PARP1是一种酶,它是对DNA损伤做出最早反应的分子之一,与多种DNA修复机制有关。
In particular, dysfunction in DNA damage response and repair is a common feature in many human cancers, including colon cancers.
特别是,DNA损伤反应和修复的功能障碍是人类许多癌症的一个共同特征,其中包括结肠癌。
Plant could repair DNA damage induced by UV-B through many methods, mainly included light-repair, base excision repair, nucleotide excision repair and recombination repair etc.
植物可以通过多种途径来修复紫外诱导的DNA损伤,主要包括光修复、碱基切除修复、核苷酸切除修复和重组修复等。
ScienceDaily (May 25, 2008) - For the first time, researchers at Delft University of Technology have witnessed the spontaneous repair of damage to DNA molecules in real time.
科学日报(08年5月25日)——代尔夫特工业大学的研究者首次对DNA分子损伤的自主修复进行实时观测。
In recent years, this method has been widely used for studies on specific classes of DNA damage, DNA specific dye, DNA repair, genetic toxicology, environmental biomonitoring and apoptosis.
近年来该技术被广泛应用于特定的DNA损伤、dna特异性染色、DNA修复、遗传毒理、环境生物监测等方面的研究。
These genes were involved in cell proliferation, gene transcription, apoptosis, signal transduction, DNA damage and repair, tumor differentiation and metastasis, cell cycle, and so on.
这些基因分别与细胞增殖、基因转录、凋亡、信号转导、DNA损伤修复、肿瘤分化和浸润转移及细胞周期调节等相关。
The breast cancer susceptibility gene, BRCA1, codes for an E3 ubiquitin ligase that functions in the maintenance of genome stability through regulation of the DNA damage response and DNA repair.
乳腺癌易感基因,BRCA1,编码一种E3泛素连接酶,BRCA1通过调控DNA损伤反应和DNA修复维持基因组的稳定性。
The SOS response of Escherichia coli is a classic model system for studying DNA damage repair response and there has been plenty of quantitative datas about it.
大肠杆菌的SOS反应作为研究DNA损伤修复反应的经典模式系统,已积累了大量观测数据。
There are several reasons why this might be, including the capacity of hypoxia to drive genomic instability and alter DNA damage repair pathways.
有很多原因可以解释,包括:乏氧驱使基因组不稳定性及改变DNA损伤修复通路的能力。
There are several reasons why this might be, including the capacity of hypoxia to drive genomic instability and alter DNA damage repair pathways.
有很多原因可以解释,包括:乏氧驱使基因组不稳定性及改变DNA损伤修复通路的能力。
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