• There also exists a cytosolic fumarase isoenzyme that is involved in DNA damage repair (3).

    存在细胞质延胡索酸水合的同工酶,参与DNA损伤修复(3)。

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  • There are several reasons why this might be, including the capacity of hypoxia to drive genomic instability and alter DNA damage repair pathways.

    很多原因可以解释,包括:驱使基因组不稳定性改变DNA损伤修复通路的能力

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  • The SOS response of Escherichia coli is a classic model system for studying DNA damage repair response and there has been plenty of quantitative datas about it.

    大肠杆菌SOS反应作为研究DNA损伤修复反应经典模式系统积累了大量观测数据。

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  • The ubiquitin-conjugating pathway involves in numerous metabolic processes in cells, including DNA damage repair, cell cycle control, stress responses and so on.

    缀合途径参与细胞多种代谢过程包括DNA损伤修复细胞周期调控应激反应等。

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  • Cell responses to ionizing radiation are determined by extent and repair capability of DNA damage. Capability of DNA damage repair and character of damage vary as a function of cell cycle.

    细胞电离辐射反应取决于DNA损伤程度细胞对此损伤的修复能力,损伤后修复能力损伤性质因细胞周期

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  • With advancement in radiobiology, the respective molecular mechanisms underlying cell kinetics alteration and DNA damage repair is being revealed gradually and takes on many obvious similarities.

    随着放射生物学研究的进展细胞动力学改变修复分子基础逐渐揭示出来,表现出许多明显共同点

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  • Deinococcus radiodurans, as a model organism in DNA damage and repair, is the most resistant bacterium to ionizing radiation.

    辐射球菌作为DNA损伤修复的典范生物电离辐射最有抵抗力细菌

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  • If the cell then botches the repair, stitching the fragments back together in a 'higgledy piggledy' fashion, the damage to its cache of DNA, leaves it ripe for the rapid development of cancer.

    如果这个细胞开始笨拙地修补,把碎片杂乱缝合起来,这样就破坏原来DNA结构,癌症的快速形成提供了条件。

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  • Shock waves create energetic subatomic particles called cosmic rays, which can tear apart biomolecules and damage DNA beyond repair.

    冲击波创造出一种叫做宇宙射线高能亚原子微粒东西撕裂生物分子DNA造成无法修复的损伤

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  • The results confirmed that the alcohol (ethanol) was being converted to acetaldehyde, causing DNA damage and switching on the cell's DNA repair genes.

    结果表明酒精(乙醇)转换乙醛破坏dna,激活细胞内dna修复基因。

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  • Normally zebrafish, which carry the same p53 gene as humans, can survive low doses of radiation, which causes damage to the DNA, because the gene steps in to repair that damage.

    在通常情况下人类一样携带相同p 53基因斑马鱼可以承受剂量放射,放射会对DNA造成损坏基因会加入对损坏的修复

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  • DNA repair is essential for the accurate preservation of genetic information and to ensure the healthy functioning of cells, and a connection between aging and DNA damage has long been suspected.

    DNA修复遗传信息准确保存确保细胞正常功能必需年龄DNA损伤关系一直存在疑问。

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  • Objective to study the DNA damage and repair of normal lung interstitial cells and human lung adenocarcinoma cells exposed to cigarette smoke.

    目的探讨香烟烟雾溶液染毒人正常细胞癌细胞的DNA损伤及其修复效应。

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  • The single cell gel electrophoresis assay is a method that can inspect the DNA damage and repair of cells which have nucleus.

    单细胞凝胶电泳技术种在单细胞水平上检测细胞DNA损伤修复方法

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  • Comparatively, as IRM-2 mice are of radioresistance, the role of DNA damage caused by radiation and damage repair can be observed directly invivo.

    相比之下,具有辐射抗性IRM - 2小鼠极好的实验对象,直接观察活体动物的辐射损伤修复

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  • Micronucleus rate, DNA damage and repair were detected by micronucleus test in vitro and single cell gel electrophoresis(assay).

    体外核试验单细胞凝胶电泳检测两种细胞微核DNA损伤修复的差异。

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  • The DNA oxidative damage is believed that it is repaired mainly by the base excision repair (BER) mechanism with many repairing enzymes.

    已知细胞中DNA氧化损伤主要通过碱基切除修复(BER)来完成,许多修复酶参与了修复过程。

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  • ObjectiveTo study the reaction of Guizhou miniature pig to the DNA damage and repair caused by chemical substances or drugs.

    目的研究贵州小型淋巴细胞化学药物引起DNA损伤修复影响反应

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  • Conclusions Some DNA replication, and damage repair genes associated with benzene poisoning show differential expression, which provides the basis for screening biomarkers of benzene poisoning.

    结论中毒患者外周血白细胞DNA复制损伤修复基因正常人相比存在差异性表达进一步筛选苯中毒生物标志物提供依据

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  • In response to DNA damage, the complex cellular mechanisms including cell cycle arrest, transcription induction and DNA repair are activated.

    为了应对DNA损伤细胞有一套复杂机制包括细胞周期停滞诱导转录DNA修复被激活。

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  • Objective To investigate the transcription-coupled repair factor CSB/ERCC6 expression and neuronal DNA damage in ischemic area after cerebral ischemia-reperfusion in rats.

    目的探讨大鼠脑缺血再灌注缺血不同时相转录修复偶联因子CSB/ERCC6 )表达神经元DNA损伤的作用。

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  • Objective To investigate the association of polymorphisms of metabolic and DNA repair enzyme genes and DNA damage in peripheral blood lymphocytes in coke-oven workers.

    目的研究外源性化学物代谢酶DNA损伤修复基因多态性焦炉作业工人外周血淋巴细胞DNA损伤易感性关系。

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  • Objective to observe the effects of zinc-deficiency (ZD) on antioxidation system and repair of DNA damage and of hepatic cells by establishing an aging mice model induced with D-galactose.

    目的通过d半乳糖诱导小鼠衰老模型探讨缺锌衰老小鼠抗氧化系统肝脏dna损伤修复影响

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  • Purpose and methods: Single cell gel electrophoresis (SCGE), sister chromatid exchanges (SCE), chromosome aberrations are three methods to determine DNA damage and repair.

    目的方法单细胞凝胶电泳技术(SCGE)、姐妹染色单体交换法(SCE)和染色体畸变分析法均能被用来检测dna损伤修复

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  • Objective To investigate the radioresistant mechanism of the newly established D6-R subline with respects to cell growth kinetics, radiation-induced apoptosis, DNA damage and repair.

    目的研究新的放射抗性肺癌D6-R细胞亚系增殖活性、放射诱导凋亡DNA损伤修复方面的特征,初步探讨D6-R细胞放射抗性的机理

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  • Objective To screen DNA replication, and damage repair genes associated with benzene poisoning by using gene expression profile analysis.

    目的筛选中毒有关DNA复制损伤修复基因

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  • Looking at cells in a dish, the team found that mistakes in these genes prevented the cells from being able to repair damage to their DNA.

    研究团队调查研究一个盘子里细胞发现这些基因的缺陷能够阻止细胞修复它们DNA损害

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  • Plant could repair DNA damage induced by UV-B through many methods, mainly included light-repair, base excision repair, nucleotide excision repair and recombination repair etc.

    植物可以通过多种途径来修复紫外诱导DNA损伤主要包括光修复、碱基切除修复、核苷酸切除修复重组修复

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  • In this study, researchers exposed lightly and darkly pigmented human melanocytes to UVA radiation and assessed DNA damage and the capacity of these cells to repair damaged DNA.

    研究中,研究人员分别将含有少量辆色素黑色素细胞置于uva辐射中,评价DNA损伤以及这些细胞修复损伤dna能力

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  • In this study, researchers exposed lightly and darkly pigmented human melanocytes to UVA radiation and assessed DNA damage and the capacity of these cells to repair damaged DNA.

    研究中,研究人员分别将含有少量辆色素黑色素细胞置于uva辐射中,评价DNA损伤以及这些细胞修复损伤dna能力

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