We show from in vitro release experiments that microsphere size has a significant effect on drug release rate. The initial release rate decreased with an increase in microsphere size.
从体外释放试验中可知微球大小对药物释放率有很大的作用。药物开始释放率与微球大小负相关。
CONCLUSION The TFH tablet has sustained release property in vitro. The drug release pattern is in accord with Weibull distribution.
结论醋柳黄酮缓释片缓释效果显著,体外释放符合威布尔分布模型。
At the same time, the influences of the drug-fed amount on PMT and release behavior in vitro of PMT were investigated.
同时,还研究了投药量对PMT的影响及PMT的体外药物释放行为。
Vitamin B12 was selected as a model drug and the in vitro release properties was studied.
以维生素b12为模型药物,研究药物的释放性质。
Methods Coating prescription was optimized by uniform design and the drug release characteristic was tested in vitro.
方法采用均匀设计优化包衣处方,对度米芬渗透泵片进行体外释放度试验。
OBJECTIVE: to prepare aspirin gastric floating capsule and to study its in vitro drug-release characteristics.
目的:制备小剂量阿司匹林胃漂浮胶囊并研究其体外释药特征。
Objective To study the preparation technique and in vitro drug release of adriamycin gelatin microspheres (ADM-GMS).
目的对阿霉素明胶微球(ADM-GMS)的制备工艺及体外释药特性进行研究。
OBJECTIVE To evaluate drug release properties in vitro of the hydrogel films made of cross-linked hyaluronic acid derivatives.
目的对交联透明质酸衍生物制备的载药水凝胶膜进行体外药物释放研究。
OBJECTIVE To study the preparation process, assay and in vitro drug release of adriamycin polylactic acid microspheres.
目的:对阿霉素聚乳酸微球的制备工艺、含量测定及体外释药特性进行初步研究。
Aim To prepare ondansetron hydrochloride osmotic pump tablets (OND-OPT) and investigate their in vitro drug release behavior.
目的制备盐酸昂丹司琼渗透泵型控释片剂(OND - OPT)并考察体外释药特性。
According to the literature, UV spectrophotometry was developed for the investigation of physicochemical properties, content and drug release in vitro.
建立了紫外分光光度法,用于盐酸氯米帕明基本理化性质、片剂释放度和含量的测定;
Aim To prepare Clarithromycin floating beads and investigate its buoyancy, entrapment efficiency and drug release behavior in vitro.
目的制备克拉霉素胃漂浮小丸,考察其漂浮性,包封率和体外释药行为。
OBJECTIVE To study the preparation of aciclovir loaded albumin microspheres (ACV BSA MS) and evaluate its morphology, drug loading and release in vitro.
目的优化阿昔洛韦白蛋白微球的制备工艺,并对其形态学性质、载药量、体外释药进行考察。
Objective To prepare aciclovir sustained-release pellets and investigate the drug release mechanism in vitro.
目的制备阿昔洛韦缓释微丸,并对其体外释药情况进行研究。
Test of weight, size, drug concentration, mechanical function and antibacterial test and in vitro release study were done to evaluate the DDS.
对DDS药棒进行重量、大小、含药量、机械性能测试和抑菌实验、体外释放实验研究。
Objective:To study the release characters in vitro of Vinpocetine self- microemulsifying drug delivery system (VIN-SEDDS).
目的:研究长春西汀自乳化释药系统(VIN-SEDDS)的体外释药特性。
Microscopic morphology, diameter and drug-loaded amount of the micelles were examined by means of TEM, DLS and UV respectively, and their in vitro drug release rates were measured.
通过透射电镜观察、动态光散射测定、紫外吸光度测定等手段分析胶束的微观形态、粒径大小和载药量、测定了载药胶束的体外释药速率。
AIM To develop a novel pulsatile drug delivery system of which the lag time is cont rolled by an erodible plug (EP) and evaluate its release characteristics in vitro.
目的制备一种由溶蚀塞控制时滞的新型脉冲给药系统并对其体外释药行为进行评价。
Results the nifedipine sustained-release beads was hydrophilic gel frame, drug diffusion and frame erosion was the release mechanisms in vitro.
结果本文自制硝苯地平缓释微丸为亲水性凝胶骨架制剂,体外释放机制包括药物扩散和骨架溶蚀两种作用。
A few of evaluation methods for drug release in vitro of sustained-controlled matrix tablets were introduced in this review.
本文简要介绍了几种缓控释骨架片药物体外释放行为的评价方法。
Objective To compare in vitro antitumor effects of controlled biodegradable drug release system and simplex anti-tumor drug in the patients with glioma.
目的比较可生物降解药物缓释体与单纯抗瘤药物体外抗胶质瘤细胞的作用。
The in vitro test of IBU loading and release illustrated the system had a great potential use for thermo-responsive controlled drug-release.
对最终体系进行的体外药物布洛芬(IBU)的装载和释放测试表明,该体系在温度响应控制药物释放方面有着较大的潜在应用前景。
OBJECTIVE:To investigate the characteristics of drug release and the factors affecting the in vitro dissolubility of diclofenac potassium double-layer tablets(DPD).
目的:考察双氯酚酸钾双层片的体外释放特征及其影响因素。
Objective:To prepare diclofenac diethylammonium gel and study the factors affecting drug release by transdermal test in vitro.
目的:制备双氯芬酸二乙胺凝胶并考察其释药影响因素。
RESULTS Using the release rate of Rhein from film as an evaluation index, the in vitro drug releases were well.
结果以膜剂中大黄酸的释放度为评价指标,膜剂体外缓释效果良好。
OBJECTIVE To establish a quality standard for Shuanghuangbu sustained release periodontal medicinal strip and investigate its in vitro drug release.
目的:建立双黄补牙周缓释药条的质量控制标准,并测定其体外释放度。
The in vitro drug release profile of the HPCD complex and liposomes entrapping cinnarizine-HPCD complex were evaluated.
评价单纯包合物和包合物脂质体的体外释放行为;
The solubility of CH331 in outer aqueous phase played a significant role in encapsulation efficiency and in vitro drug release of microspheres.
CH331在外水相中的溶解度影响微球的包封率和体外释药行为。
The pattern of drug release for 30 days in vitro fitted to zero order release plot, with an initial burst effect at the first day.
体外释放第一天呈突释效应,而后药物释放基本符合零级动力学过程。
The drug loading rate, encapsulation efficiency, particle distribution and in vitro release of Lac-NCTD from liposomes were investigated, respectively.
考察了药物与磷脂的复合率,磷脂复合物脂质体的包封率,粒径大小和分布,以及体外释药特性。
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