ObjectiveTo prepare and determine the content and entrapment efficiency of Hydroquinone liposome.
目的制备氢醌脂质体并测定含量及包封率。
OBJECTIVE To evaluate the quality of astragaloside liposome and determine its entrapment efficiency.
目的对黄芪皂苷脂质体进行质量评价,测定黄芪皂苷脂质体的包封率。
The entrapment efficiency, drug load content, in vitro release and stability of Bre-CS-NP were studied.
并进行了灯盏花素壳聚糖纳米粒包封率、载药量、体外释放度、稳定性等试验研究。
METHODS Liposme was prepared with different method, using entrapment efficiency as the optimized indexes.
方法以包封率为主要指标,对不同制备方法进行考察。
Results: The ammonium sulfate gradient method was used to prepare CPT-11 and get higher entrapment efficiency 75.
结果:硫酸铵梯度法制备的盐酸伊立替康脂质体包封率较高75。
RESULTS The entrapment efficiency with passive loading was only 13.3%; while up to 84.6% with active loading method.
结果被动载药法得到的包封率仅有13.3%,主动载药法的包封率最高可达84 . 6 %。
ResultsThe entrapment efficiency with passive loading method was low, while up to 84.38% with active loading method.
结果被动载药法制备脂质体包封率较低,主动载药制备脂质体包封率为84.38%。
OBJECTIVE To prepare vincristine sulfate liposomes and to develop a method for determining its entrapment efficiency.
目的制备硫酸长春新碱脂质体,建立包封率测定方法。
Aim To prepare Clarithromycin floating beads and investigate its buoyancy, entrapment efficiency and drug release behavior in vitro.
目的制备克拉霉素胃漂浮小丸,考察其漂浮性,包封率和体外释药行为。
OBJECTIVE To establish an RP-HPLC method for determining the content of puerarin in Puerarin long circulating liposome and its entrapment efficiency.
目的建立RP-HPLC法测定葛根素长循环脂质体中葛根素的含量和包封率。
The results indicated that the microspheres had poor drug loading and entrapment efficiency abilities due to residual impurities contained in polymer.
初步分析表明,因聚合物中残留的微小杂质的影响,造成了所制备的载药微球过低的载药量及包封率。
OBJECTIVE To prepare vincristine sulfate liposomes by active loading method, and study the influence of different factors on the entrapment efficiency.
目的采用主动载药法制备硫酸长春新碱脂质体,考察包封率的影响因素。
Optimization of preparation and formulation was accomplished by evaluating the drug-loading amounts and the entrapment efficiency of luteolin liposomes.
方法采用薄膜分散法和冻干工艺进行木犀草素脂质体制备,并以载药量、包封率为评价指标,优化制备处方和工艺。
METHODS The effect of cholesterol content, lipid-drug ratio, incubation time and temperature, and calcium acetate concentration on entrapment efficiency was studied.
方法以包封率为指标,考察阿魏酸脂质体胆固醇含量、脂药比、孵育时间、孵育温度、钙离子浓度等因素对包封率的影响。
It also describes the quality of the evaluation of liposome several indicators, such as shape, size, entrapment efficiency stability, detection methods at home and abroad.
另外还介绍了评价脂质体质量的几个指标,如形状大小、包封率、稳定性检测方法的国内外研究进展。
The drug loading, entrapment efficiency, diameter of nanoparticles and particle diameter distribution, shape and release curve of nanoparticles were investigated in vitro.
对纳米粒的载药量、大小及分布、形态及体外释放等进行了研究。
Podophyllotoxin SLN has high entrapment efficiency, an even distribution in size and a satisfactory stability, indicating that it might be a hopeful skin topical preparation in.
鬼臼毒素sln具有较高的包封率,纳米粒粒径分布均匀,稳定性较好,可能制成一种有希望的皮肤外用制剂。
OBJECTIVE To establish a method for determining carboplatin content and entrapment efficiency of thermo-sensitive liposomes and to study temperature-sensitive release property in vitro.
目的建立卡铂热敏脂质体包封率和含量测定方法,并对其体外热敏释药特性进行考察。
ABSTRACT:OBJECTIVE To establish a method to determine thermo-sensitive liposome of carboplatin content and entrapment efficiency. Study release property of temperature-sensitive in vitro.
摘要:目的建立卡铂热敏脂质体包封率和含量测定方法,并对其体外热敏释药进行考察。
Conclusion: The HCPT-SSLN has high entrapment efficiency and drug loading, uniform particle size, good stability, which initially indicates that HCPT is fit for being incorporated into SSLN.
结论:本实验制备的HCPT - SSLN包封率和载药量较高,粒径分布均匀,稳定性良好。初步表明HCPT适合进行SSLN包裹。
Results Free drugs could be effectively separated from the Hup ASLN by ultrafiltration. The average entrapment efficiency of three batches of Hup ASLN was 57.63%, with the recovery of 98.09%.
结果超滤法能有效地将石杉碱甲固体脂质纳米粒与游离石杉碱甲分离,回收率为98.09%,测得3批样品的平均包封率为57.63%。
Objectives: To prepare epirubicin hydrochloride liposomes(Epi-lip), establish an HPLC method for the determination of EPI and to optimize the method for determination of entrapment efficiency(EE%).
目的:制备盐酸表阿霉素脂质体,建立HPLC含量测定方法并优选包封率测定方法。
CONCLUSION the method is convenient, accurate and suitable for determining the content and entrapment efficiency of carboplatin liposomes. Carboplatin liposomes are temperature-sensitive remarkably.
结论本方法简便、准确,可以用于测定卡铂脂质体的含量和包封率,所制备的热敏脂质体具有显著的热敏释药特性。
CONCLUTION the method is convenient, accurate and suitable for determining the content and entrapment efficiency of carboplatin liposome. Liposomes of carboplatin are temperature-sensitive remarkably.
结论本方法简便、准确,可以用于测定卡铂脂质体的含量和包封率,所制得的热敏脂质体具有显著的热敏释药特性。
CONCLUTION the method is convenient, accurate and suitable for determining the content and entrapment efficiency of carboplatin liposome. Liposomes of carboplatin are temperature-sensitive remarkably.
结论本方法简便、准确,可以用于测定卡铂脂质体的含量和包封率,所制得的热敏脂质体具有显著的热敏释药特性。
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