Satava says, "We are in the midst of a fundamental change in the field of medicine."
萨塔瓦说：“我们正处于医学领域的根本变革之中。”
Industrialization not only produced a fundamental change in the way work was organized; it transformed the very nature of work.
工业化不仅从根本上改变了工作的组织方式，还改变了工作的本质。
The cumulative effect was a fundamental change in how millions of people approached life itself, a reversal of attitude that must rank as one of the largest in human history.
这种累积效应对数百万人对待生活本身的态度产生了根本性的改变，这种态度的逆转肯定是人类历史上最大的一次。
As many office workers adapt to remote work, cities may undergo fundamental change if offices remain under-utilized.
随着许多上班族适应远程办公，如果办公室仍然被闲置，那我们的城市可能会发生根本性的变化。
I still look on UK as being perhaps the best hope for leading a fundamental change.
我始终认为英国也许最有希望引领根本变革。
Much more needs to be done for the new leadership to bring about this fundamental change.
更多的是需要新任领导为我们带来这一根本变化。
But in roughly 15 to 20 years, a fundamental change will take place in this competitive race.
但未来的15到20年间，在这场竞争激烈的比赛中会产生重大的变化。
Hung Taiji's reign also saw a fundamental change of policy towards his han Chinese subjects.
洪太极的统治地位也从根本上改变他的政策的汉人科目。
The urgency of providing doctors for underserved populations demands more fundamental change.
迫切需要为缺医少药的人群提供医生，所以必须作出更加彻底的变革。
However, that is not a fundamental change; it has just improved the efficiency of an existing process.
然而，这不是根本的变化，只是提高了现有交易的效率。
We have a very big problem, only to worsen if we don't start seriously thinking about fundamental change.
我们有个很严重的问题，如果不开始严肃思考根本的变革，它只会越发严重。
This is a fundamental change from the multi-master replication model that we've been discussing thus far.
这是与我们目前为止一直讨论的多主机复制模型最根本的不同。
And this step requires a fundamental change in policy support from export oriented to domestic consumer growth.
这需要实现政策的根本性转变，即从支持外向型经济向支持内向型经济转变。
There is potential for a fundamental change in the way we provide treatment for chronic diseases in older people.
有可能根本改变我们治疗中老年人慢性疾病的方法。
Rather, it was a fundamental change in the technology the Mesopotamians used to produce food: the adoption of the plough.
相反地，是美索不达米亚常常生产食物的技术的一个基本改变——犁的采用，导致了社会的转变。
The rise of Facebook is more than just a fundamental change in the way we use the Internet, it's a collision of cultures.
Facebook的兴起远非我们使用互联网方式的根本性改变那么简单，这是一种文化的崩塌。
Repeating old mantras in the face of fundamental change is natural, because making that change is really, really hard.
面对根本性变革的时候总要不断重复这些理论，因为变革是一件非常困难的事情。
But with the introduction of Buddhism into Japan in the sixth century, the pagoda underwent a fundamental change in design.
但是，在六世纪佛教传入到日本后，宝塔却在设计上发生了根本性变化。
The fundamental change to the catalog controller was changing to cached proxy from the legacy catalog implementation, as follows
对Catalog控制器的根本更改是，从遗留 Catalog实现更改到了缓存代理，如下所示
This change is controversial because some feel that the modest benefit to mainframe users is not worth such a fundamental change.
这种变化存在争议，有人认为对大型机用户带来的有限好处不值得做这种基础性的改变。
The move, the most fundamental change in the site’s four-year history, has excited advertisers but irked many of its 50m users.
此举尽管让广告商欢呼雀跃，却令该网站5千万用户中的许多人感到不满。
But he vowed that the island will not see fundamental change even after he and his older brother and predecessor Fidel Castro are gone.
但是，他也发誓，即使他和他的哥哥卡斯特罗不在了，这个岛国不会发生根本变化。
In some cases, they realize too late that a more fundamental change is needed: a change of processes, organizations, and, yes, culture.
有些情况下，他们很晚才意识到需要进行根本性变革：流程、机构以及(不错)文化变革。
This will inevitably invoke industrial upgrading, readjustment of industrial structure and fundamental change of economic growth form.
这必将引发产业升级、产业结构的大调整和经济增长方式的根本性改变。
First, it's that I believe that if there isn't a fundamental change in the supply change in the company there, it's simply a financial move.
首先，我相信这不是，供应领域的对基础的变动，在公司里，这只是一个经济改变。
I don't mean to suggest that all problems have been solved. But a fundamental change has indeed taken place, and that is what counts most.
不是说所有的问题统统解决了，但是发生了一个根本的转变，这是最重要的事实。
I don't mean to suggest that all problems have been solved. But a fundamental change has indeed taken place, and that is what counts most.
不是说所有的问题统统解决了，但是发生了一个根本的转变，这是最重要的事实。
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