OBJECTIVE To provide biological pharmaceutical basis for dosage forms design of harmine hydrochloride by studying its absorption kinetics in various intestinal segments of rat.
目的研究盐酸去氢骆驼蓬碱在大鼠胃肠道各段的吸收动力学特征，为其剂型设计提供生物药剂学依据。
OBJECTIVE To study the plasma protein binding rate of harmine hydrochloride.
目的：测定盐酸去氢骆驼蓬碱的血浆蛋白结合率。
Objective To prepare a harmine hydrochloride liposome formulation with high encapsulation efficiency.
目的制备高包封率的盐酸去氢骆驼蓬碱脂质体。
Method the absorption kinetics of harmine hydrochloride from duodenum, jejunum, ileum, and colon were investigated using in situ perfusion method in the rats.
方法采用大鼠在体肠循环法分别研究盐酸去氢骆驼蓬碱在大鼠十二指肠、空肠、回肠及结肠中的吸收动力学特征。
Method the absorption kinetics of harmine hydrochloride from duodenum, jejunum, ileum, and colon were investigated using in situ perfusion method in the rats.
方法采用大鼠在体肠循环法分别研究盐酸去氢骆驼蓬碱在大鼠十二指肠、空肠、回肠及结肠中的吸收动力学特征。
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