An anti-HB-EGF antibody having an internalizing activity is disclosed.
本发明公开了一种具有内化活性的抗hb - EGF抗体。
A cytotoxic substance is preferably bound to the anti-HB-EGF antibody of the present invention.
优选地，本发明的抗hb - EGF抗体结合有细胞毒性物质。
Objective to investigate the role of heparin binding epidermal growth factor-like growth factor (HB-EGF) in active psoriasis vulgaris.
目的探讨肝素结合表皮生长因子样生长因子(HB - EGF)在银屑病发病早期中的作用机制。
Methods HB-EGF in normal tissues, tissues adjacent to cancer and skin squamous cell carcinoma lesions were detected by immunohistochemistry.
方法用免疫组化的方法检测正常组织，癌旁组织和鳞状细胞癌皮损中hb EGF蛋白表达。
HB-EGF is a member of EGF family, which is expressed in various tissues and cells, and involves in many pathologic and physiological processes.
肝素结合表皮生长因子(HB - EGF)是EGF家族的成员之一，可以在多种组织和细胞中表达，参与多种病理生理过程。
Objective to construct heparin-binding epidermal growth factor-like growth factor transgenic mice in order to investigate the role of HB-EGF in the fibrosis of tissues.
目的建立系统表达肝素结合性表皮生长因子的转基因动物模型，利用转基因动物模型研究HB - EGF与组织纤维化的关系。
Chinese Herbs may enhance expression of HB-EGF on trophoblast through autocrine and paracrine role, and may enhance proliferation, invasion and tolerance anoxia of trophoblast.
中药可能通过自分泌或旁分泌增加滋养细胞HB - EGF表达，增强滋养细胞的增殖及侵入和对缺氧的耐受。
Percutaneous sacral third nerve root neurostimulation improves symptoms and normalizes urinary HB-EGF levels and antiproliferative activity in patients with interstitial cystitis.
经皮骶骨第三脑神经根神经刺激改善间质性膀胱炎患者症状和使尿hb - EGF水平及抗增殖活性恢复正常。
Percutaneous sacral third nerve root neurostimulation improves symptoms and normalizes urinary HB-EGF levels and antiproliferative activity in patients with interstitial cystitis.
经皮骶骨第三脑神经根神经刺激改善间质性膀胱炎患者症状和使尿hb - EGF水平及抗增殖活性恢复正常。
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